NNCI: Soft Hybrid Nanotechnology Experimental (SHyNE) Resource

NNCI：软混合纳米技术实验 (SHyNE) 资源

• 批准号: 2025633
• 负责人: Vinayak Dravid
• 金额: $ 550万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2025633&HistoricalAwards=false
• 关键词: NNCI; Soft; Hybrid; Nanotechnology; Experimental

Non-Technical Description:The Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource NNCI site is the Northwestern University (NU) led collaborative venture with the Pritzker Nanofabrication Facility (PNF) of the University of Chicago (UC). SHyNE builds on each institution's long history of transforming the frontiers of science and engineering. Soft nanostructures are typically polymeric, biological, and fluidic, while hybrid represents systems comprising structures and hybrid materials comprising soft-hard interfaces. SHyNE facilities provides broad access to an extensive fabrication, characterization, and computational infrastructure with a multi-faceted and interdisciplinary approach for transformative science and enabling technologies. SHyNE provides specialized capabilities for soft materials and soft-hard hybrid nano-systems. SHyNE enhances regional capabilities by providing users with on-site and remote open-access to state-of-the-art laboratories and world-class technical expertise to help solve the challenging problems in nanotechnology research and development. SHyNE covers non-traditional industries: agricultural, biomedical, chemical, food, geological and environmental, among others. A critical component of the SHyNE mission is scholarly outreach through secondary and post-secondary research experience and integration with course/curricula as well as societal and public outreach through a novel nano-journalism project in collaboration with the Medill School of Journalism. SHyNE promotes and facilitates active participation of underrepresented groups, including women and minorities, in sciences and utilizes Chicago's public museums for broader community outreach. SHyNE leverages an exceptional depth of intellectual, academic, and facilities resources to provide critical infrastructure in support of research, application development, and problem-solving in nanoscience and nanotechnology and integrates this transformative approach into the societal fabric of Chicago and the greater Midwest.Technical Description:SHyNE is a solution-centric, open-access collaborative initiative with strong ties with Northwestern University's International Institute for Nanotechnology (IIN), in partnership with University of Chicago's Pritzker School of Molecular Engineering. SHyNE open-access user facilities bring together broad experience and capabilities in traditional soft nanomaterials such as biological, polymeric or fluidic systems and hybrid systems combining soft/hard materials and interfaces. Collectively, soft and hybrid nanostructures represent remarkable scientific and technological opportunities. However, given the sub-100nm length-scale and related complexities, advanced facilities are needed to harness their full potential. Such facilities require capabilities to pattern soft/hybrid nanostructures across large areas and tools/techniques to characterize them in their pristine states. These divergent yet integrated needs are met by SHyNE, as it coordinates Northwestern's extensive cryo-bio, characterization and soft-nanopatterning capabilities with the state-of-the-art cleanroom fabrication and expertise also at UC's Pritzker Nanofabrication Facility (PNF). SHyNE addresses emerging needs in synthesis/assembly of soft/biological structures and integration of classical clean-room capabilities with soft-biological structures, providing expertise and instrumentation related to the synthesis, purification, and characterization of peptides and peptide-based materials. SHyNE coordinates with Argonne National Lab facilities and leverages existing super-computing and engineering expertise under Center for Hierarchical Materials Design (CHiMaD) and Digital Manufacturing and Design Innovation Institute (DMDII), respectively. An extensive array of innovative educational, industry and societal outreach, such as nano-journalism, industry-focused workshops/symposia and collaborations with Chicago area museums, provide for an integrated and comprehensive coverage of modern infrastructure for soft/hybrid systems for the next generation researchers and the broader society.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术描述：软混合纳米技术实验（SHyNE）资源NNCI站点是西北大学（NU）领导的与芝加哥大学（UC）普利兹克纳米制造设施（PNF）的合作企业。SHyNE建立在每个机构改变科学和工程前沿的悠久历史之上。软纳米结构通常是聚合物、生物和流体，而混合纳米结构代表由结构和混合材料组成的系统，包括软硬界面。SHyNE设施为变革性科学和使能技术提供广泛的制造、表征和计算基础设施，采用多方面和跨学科的方法。SHyNE提供软材料和软硬混合纳米系统的专业能力。SHyNE通过为用户提供现场和远程开放访问最先进的实验室和世界一流的技术专长来增强区域能力，帮助解决纳米技术研究和开发中的具有挑战性的问题。该公司涵盖农业、生物医药、化工、食品、地质和环境等非传统行业。SHyNE使命的一个重要组成部分是通过中学和大专研究经验进行学术推广，并与课程/课程相结合，以及通过与Medill新闻学院合作的新颖纳米新闻项目进行社会和公众推广。SHyNE促进和促进包括妇女和少数民族在内的代表性不足的群体积极参与科学，并利用芝加哥的公共博物馆进行更广泛的社区外展。SHyNE利用卓越的智力、学术和设施资源深度，为纳米科学和纳米技术的研究、应用开发和问题解决提供关键基础设施支持，并将这种变革方法整合到芝加哥和中西部地区的社会结构中。技术描述：SHyNE是一个以解决方案为中心的开放获取合作计划，与西北大学国际纳米技术研究所（IIN）以及芝加哥大学普利兹克分子工程学院建立了紧密的合作关系。SHyNE开放访问用户设施汇集了传统软纳米材料（如生物，聚合物或流体系统）和结合软/硬材料和界面的混合系统的广泛经验和能力。总的来说，软纳米结构和混合纳米结构代表着非凡的科学和技术机遇。然而，考虑到100nm以下的长度尺度和相关的复杂性，需要先进的设施来充分利用其潜力。这样的设施需要在大范围内对软/混合纳米结构进行建模的能力，以及在原始状态下对其进行表征的工具/技术。SHyNE可以满足这些不同但又综合的需求，因为它将西北大学广泛的冷冻生物、表征和软纳米图案能力与最先进的洁净室制造和加州大学普利兹克纳米制造设施（PNF）的专业知识相结合。SHyNE解决了软/生物结构合成/组装的新兴需求，并将经典的洁净室能力与软生物结构相结合，提供与肽和肽基材料的合成、纯化和表征相关的专业知识和仪器。SHyNE与阿贡国家实验室设施协调，并利用分层材料设计中心（CHiMaD）和数字制造与设计创新研究所（DMDII）现有的超级计算和工程专业知识。一系列创新的教育、工业和社会外展活动，如纳米新闻、以工业为重点的研讨会/专题讨论会以及与芝加哥地区博物馆的合作，为下一代研究人员和更广泛的社会提供了对软/混合系统的现代基础设施的综合和全面的覆盖。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Structurally dynamic crystalline 1D coordination polymers enabled via the Weak-Link Approach

• DOI: 10.1016/j.poly.2022.116116
• 发表时间: 2022-09-15
• 期刊: POLYHEDRON
• 影响因子: 2.6
• 作者: Coleman, Benjamin D.;d'Aquino, Andrea I.;Mirkin, Chad A.
• 通讯作者: Mirkin, Chad A.

A General DNA-Gated Hydrogel Strategy for Selective Transport of Chemical and Biological Cargos

• DOI: 10.1021/jacs.1c08114
• 发表时间: 2021-10-06
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Gu, Yuwei;Distler, Max E.;Mirkin, Chad A.
• 通讯作者: Mirkin, Chad A.

Nanoparticle Superlattices through Template-Encoded DNA Dendrimers

• DOI: 10.1021/jacs.1c07858
• 发表时间: 2021-10-11
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Cheng, Ho Fung;Distler, Max E.;Mirkin, Chad A.
• 通讯作者: Mirkin, Chad A.