MRI: Acquisition of a 400 MHz NMR Spectrometer for Expanding Research and Research Training at San Francisco State University

旧金山州立大学(SFSU)被授予购买400 MHz核磁共振光谱仪，以扩大五所非博士授予机构的研究能力和培训：旧金山州立大学、圣何塞州立大学、索诺马州立大学、加州州立大学东湾和加利福尼亚州多米尼加大学。该奖项将为教职员工、学生和研究人员提供获得最先进仪器的机会，以扩大化学和生命科学前沿的研究。它将进一步支持正在进行的将高水平研究纳入教学环境的机构努力，为美国一些种族和文化最多元化的大学的学生提供获得复杂仪器和丰富研究的学习环境的机会。该奖项提供的增强的研究能力也将成为吸引学生进入STEM领域并招聘专职教师的工具，从而增加致力于统一研究和教学的教师-学者队伍。400 MHz光谱仪的实践培训将使本科生和硕士学生为博士项目和职业生涯做好准备，使他们能够培养在博士项目和快速发展的、技术驱动的劳动力中取得成功所必需的核心能力。总体而言，该奖项将为我们的毕业生提供技能，以应对科学专业人员面临的挑战和前景。400 MHz核磁共振光谱仪将配备一个多核宽带氟观察探头、一个超高灵敏度多核冷冻探头、一个变温装置和一个样品转换器，这将为主要是本科院校的教职员工提供接触尖端技术的途径。它将能够表征复杂的分子结构，有助于在众多研究领域取得进展，并极大地丰富学生在核磁共振光谱学方面的教育。具体地说，它将导致化学和生命科学的下列关键领域的新发现：天然产品化学；生物科学；蛋白质动力学、动力学和结构/功能；生物地球化学和晶体生长/材料化学。这一最先进的仪器将促进初级教员的职业生涯，包括代表性不足的科学家和女性科学家，并促进与I研究机构的研究人员的重要合作。它将支持与当地行业和附近大学的接触，为他们提供至关重要的核磁共振设备和培训。此外，400兆赫系统将在支持机构研究生产力、保持教育质量和外延、吸引新的教员和推出新的研究方向方面发挥重要作用。低温探头具有非凡的灵敏度，可提供高信噪比并大幅缩短实验时间，这将使教职员工和学生在他们的科学研究中取得新的突破，从而改变参与机构的研究。

An award is made to San Francisco State University (SFSU) to purchase a 400 MHz NMR spectrometer to expand research capacity and training at five non Ph.D. granting institutions: SFSU, San Jose State University, Sonoma State University, California State University East Bay, and Dominican University of California. The award will provide faculty, students, and staff researchers access to state-of-the-art instrumentation to expand research at the frontier of the chemical and life sciences. It will further support the ongoing institutional efforts to integrate high-level research into the teaching environment, providing students at some of the nation's most ethnically and culturally diverse universities with access to sophisticated instrumentation and research-enriched learning environments. The enhanced research capabilities provided by the award will also serve as a vehicle to attract students to STEM fields and to recruit dedicated faculty, thereby increasing the pool of teacher-scholars who are committed to unifying research and teaching. Hands-on training on the 400 MHz spectrometer will prepare undergraduate and Masters degree students for doctoral programs and professional careers by enabling them to develop the core competencies necessary for success in Ph.D. programs and in the rapidly-evolving, technically-driven workforce. Collectively, the award will provide our graduates with the skills to meet the challenges and prospects facing science professionals. The 400 MHz NMR spectrometer will be equipped with a multinuclear broadband fluorine observe probe, an ultra-high sensitivity multinuclear cryoprobe, a variable-temperature unit, and a sample changer, which will provide faculty, students, and staff members at primarily undergraduate institutions access to cutting-edge technology. It will enable the characterization of complex molecular structures, contribute to advancements in a myriad of research fields, and significantly enrich student education in NMR spectroscopy. Specifically, it will lead to new discoveries in the following keys areas of the chemical and life sciences: natural products chemistry; biological sciences; protein kinetics, dynamics and structure/function; biogeochemistry and crystal growth/materials chemistry. The state-of-the-art instrument will promote the careers of junior faculty, including underrepresented and female scientists, and foster important collaborations with investigators at research I institutions. It will support outreach to local industries and nearby colleges, providing them access to vitally important NMR equipment and training. Moreover, the 400 MHz system will be of great importance in supporting institutional research productivity, maintaining educational quality and outreach, attracting new faculty, and launching novel research directions. The exceptional sensitivity of the cryoprobe that provides high signal-to-noise ratios and drastically reduced experiment times, will transform research at the participating institutions by enabling faculty, staff and students to break new grounds in their scientific inquiries.