MRI: Acquisition of a 400 MHz NMR Spectrometer for Expanding Research and Research Training at San Francisco State University

旧金山州立大学（SFSU）获得了一项购买400 MHz核磁共振光谱仪的奖励，以扩大其在五个非博士学位授予机构的研究能力和培训：SFSU，圣何塞州立大学，索诺玛州立大学，加州州立大学东湾和加州多米尼加大学。该奖项将为教职员工、学生和研究人员提供最先进的仪器，以扩大化学和生命科学前沿的研究。它将进一步支持正在进行的机构努力，将高水平的研究融入教学环境，为美国一些种族和文化最多样化的大学的学生提供先进的仪器和丰富的研究学习环境。该奖项提供的增强研究能力也将作为吸引学生进入STEM领域和招募专门教师的工具，从而增加致力于统一研究和教学的教师学者的数量。400兆赫光谱仪的实践培训将使本科生和硕士研究生为博士课程和职业生涯做好准备，使他们能够培养在博士课程和快速发展的技术驱动的劳动力中取得成功所必需的核心能力。总的来说，该奖项将为我们的毕业生提供技能，以应对科学专业人士面临的挑战和前景。400 MHz核磁共振光谱仪将配备多核宽带氟观察探针、超高灵敏度多核冷冻探针、可变温度单元和样品转换器，这将为主要本科院校的教职员工、学生和工作人员提供尖端技术。它将使复杂分子结构的表征，促进无数研究领域的进步，并显著丰富学生在核磁共振波谱学方面的教育。具体来说，它将导致化学和生命科学的以下关键领域的新发现：天然产物化学；生物科学;蛋白质动力学、动力学和结构/功能；生物地球化学和晶体生长/材料化学。这台最先进的仪器将促进初级教师的职业发展，包括代表性不足的女性科学家，并促进与研究机构研究人员的重要合作。它将支持与当地工业和附近大学的联系，为他们提供至关重要的核磁共振设备和培训。此外，400兆赫系统在支持院校的研究生产力、维持教育质素和推广、吸引新教员和推出新的研究方向等方面，将发挥重要作用。低温探针的高灵敏度提供了高信噪比，大大减少了实验时间，将改变参与机构的研究，使教职员工和学生在他们的科学研究中开辟新的领域。

An award is made to San Francisco State University (SFSU) to purchase a 400 MHz NMR spectrometer to expand research capacity and training at five non Ph.D. granting institutions: SFSU, San Jose State University, Sonoma State University, California State University East Bay, and Dominican University of California. The award will provide faculty, students, and staff researchers access to state-of-the-art instrumentation to expand research at the frontier of the chemical and life sciences. It will further support the ongoing institutional efforts to integrate high-level research into the teaching environment, providing students at some of the nation's most ethnically and culturally diverse universities with access to sophisticated instrumentation and research-enriched learning environments. The enhanced research capabilities provided by the award will also serve as a vehicle to attract students to STEM fields and to recruit dedicated faculty, thereby increasing the pool of teacher-scholars who are committed to unifying research and teaching. Hands-on training on the 400 MHz spectrometer will prepare undergraduate and Masters degree students for doctoral programs and professional careers by enabling them to develop the core competencies necessary for success in Ph.D. programs and in the rapidly-evolving, technically-driven workforce. Collectively, the award will provide our graduates with the skills to meet the challenges and prospects facing science professionals. The 400 MHz NMR spectrometer will be equipped with a multinuclear broadband fluorine observe probe, an ultra-high sensitivity multinuclear cryoprobe, a variable-temperature unit, and a sample changer, which will provide faculty, students, and staff members at primarily undergraduate institutions access to cutting-edge technology. It will enable the characterization of complex molecular structures, contribute to advancements in a myriad of research fields, and significantly enrich student education in NMR spectroscopy. Specifically, it will lead to new discoveries in the following keys areas of the chemical and life sciences: natural products chemistry; biological sciences; protein kinetics, dynamics and structure/function; biogeochemistry and crystal growth/materials chemistry. The state-of-the-art instrument will promote the careers of junior faculty, including underrepresented and female scientists, and foster important collaborations with investigators at research I institutions. It will support outreach to local industries and nearby colleges, providing them access to vitally important NMR equipment and training. Moreover, the 400 MHz system will be of great importance in supporting institutional research productivity, maintaining educational quality and outreach, attracting new faculty, and launching novel research directions. The exceptional sensitivity of the cryoprobe that provides high signal-to-noise ratios and drastically reduced experiment times, will transform research at the participating institutions by enabling faculty, staff and students to break new grounds in their scientific inquiries.