REU Site: Cell and Molecular Visualization at Brandeis University

REU 网站：布兰迪斯大学细胞和分子可视化

• 批准号: 1658704
• 负责人: Susan Lovett
• 金额: $ 34.17万
• 依托单位: Brandeis University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-05-15 至 2020-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1658704&HistoricalAwards=false
• 关键词: REU; Site; Cell; Molecular; Visualization

This REU Site award to Brandeis University, located in Waltham, MA will support the training of 10 students for 10 weeks during the summers of 2017- 2019 in biological research employing modern cell and molecular visualization techniques. This program, encompassing over 50 faculty in the Life Sciences, will introduce undergraduate students to a broad range of topics concerning biological structure and function. Students will conduct full-time research guided by their mentors and will participate in weekly lunch seminars, which will include faculty research presentations and professional development activities such as panel discussion with students and postdoctoral fellows from the Greater Boston area concerning careers in biotechnology, research, education, and policy. There will be group discussions of ethical issues and mentoring in science. Students will write a synopsis of their summer project, with feedback and editing, and will participate in a capstone symposium including poster presentations. Participants will be selected from a nation-wide pool based on academic record, recommendations, and potential for research in biology and should be current freshmen, sophomores or juniors at a college or university. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities, will be trained in the program which welcomes students from underrepresented groups in science. Training will take place in a supportive and interactive environment, and the participating faculty have a strong record of mentoring undergraduates in research and publishing with student co-authors. Students will have an opportunity to interact with scientists with diverse interests, at different stages in their careers, to learn how research is done. Many students will present their work at scientific conferences.A common web-based assessment tool used by all REU Site programs funded by the Division of Biological Infrastructure will be used to determine the effectiveness of the training program. Students will be tracked after the program in order to determine their career paths. Students will be asked to respond to an automatic email sent via the NSF reporting system. More information about the program is available by visiting http://www.bio.brandeis.edu/undergrad/summerResearch/ or by contacting the PI (Dr. Susan Lovett at [e-mail]) or the co-PI (Dr. Paradis at [e-mail]).

这个REU网站奖布兰代斯大学，位于马萨诸塞州沃尔瑟姆将支持10名学生在2017年至2019年的夏天在生物学研究采用现代细胞和分子可视化技术的培训10周。该计划包括生命科学领域的50多名教师，将向本科生介绍有关生物结构和功能的广泛主题。学生将在导师的指导下进行全职研究，并将参加每周的午餐研讨会，其中包括教师研究报告和专业发展活动，如与大波士顿地区的学生和博士后研究员就生物技术，研究，教育和政策的职业进行小组讨论。将有关于伦理问题和科学指导的小组讨论。学生将写他们的暑期项目的概要，反馈和编辑，并将参加一个顶点研讨会，包括海报演示。参与者将从全国范围内的游泳池根据学术记录，建议，并在生物学研究的潜力，应该是目前的新生，大学生或大三学生在学院或大学。预计共有30名学生，主要来自研究机会有限的学校，将接受该计划的培训，该计划欢迎来自科学领域代表性不足的群体的学生。培训将在一个支持和互动的环境中进行，参与的教师在指导本科生与学生合著者进行研究和出版方面有着良好的记录。学生将有机会与不同兴趣的科学家互动，在他们职业生涯的不同阶段，学习如何进行研究。许多学生将在科学会议上展示他们的工作。由生物基础设施司资助的所有REU网站项目使用的一个通用的基于网络的评估工具将用于确定培训计划的有效性。学生将在课程结束后进行跟踪，以确定他们的职业道路。学生将被要求通过NSF报告系统自动发送电子邮件。有关该计划的更多信息，请访问http://www.bio.brandeis.edu/undergrad/summerResearch/或联系PI（Susan Lovett博士，[e-mail]）或联合PI（帕拉迪斯博士，[e-mail]）。

项目成果

Identifying Small Molecules That Promote Quasipalindrome-Associated Template-Switch Mutations in Escherichia coli

鉴定促进大肠杆菌中准配体相关模板转换突变的小分子

• DOI: 10.1534/g3.120.401106
• 发表时间: 2020
• 期刊: G3: Genes|Genomes|Genetics
• 作者: Klaric, Julie A.;Perr, Eli L.;Lovett, Susan T.
• 通讯作者: Lovett, Susan T.

Stimulation of Replication Template-Switching by DNA-Protein Crosslinks

DNA-蛋白质交联刺激复制模板转换

• DOI: 10.3390/genes10010014
• 发表时间: 2019
• 期刊: Genes
• 影响因子: 3.5
• 作者: Laranjo, Laura T.;Klaric, Julie A.;Pearlman, Leah R.;Lovett, Susan T.
• 通讯作者: Lovett, Susan T.