Technician Training in Gene Editing

CRISPR/Cas9基因编辑迅速扩展到生物医学研究的每个子学科，需要对合格的技术人员进行相应的培训。基因编辑技术人员培训（TTiGE）项目通过特拉华州技术社区学院（DTCC）的教师和基因编辑研究所（GEI）的科学家之间的合作来解决这一需求。通过这种伙伴关系，GEI研究环境中使用的基因编辑的最新技术和应用将被整合到DTCC生物技术计划的几门课程中以学生为中心的课程中。然后，这些活动将通过基因编辑技术指导讲习班在全国范围内传播给社区大学教师。还将提供在课堂上使用高影响力教学的培训，这已被证明对STEM课程的保留有重大影响。通过培训讲师，接受CRISPR基因编辑技术培训的学生人数有可能支持全国各地的生物科学公司和研究实验室增加基因编辑的使用。TTiGE项目的目标是增加掌握CRISPR/Cas9基因编辑和相关技能的生物技术人员的数量。一名GEI技术人员将获得支持，将基因编辑技术知识和进展转移给DTCC教师，DTCC教师将创建高影响力的课程，并将其纳入生物技术计划的几个课程中。该计划进一步加强了生物技术计划，该计划通过积极学习和本科生研究的结合而得到加强（奖项# 1003649）。将开发为期两天和五天的研讨会，以培训社区大学教师在酵母和哺乳动物细胞中的基因编辑技术以及以学生为中心的课程的使用。后续沟通将为研讨会与会者提供技术和教育支持，并传播该领域的最新技术进步。项目评估将衡量对特拉华州理工学生的影响，并跟踪研讨会与会者将材料纳入课程的情况。以学生为中心的教学法的教师培训将建立教师信心，将这些做法扩展到其他课程，以提高生物科学学生的保留率和毕业率。TTiGE项目的基因编辑重点确保技术人员毕业时掌握关键的入门级技能，并丰富了就业技能。

The rapid expansion of CRISPR/Cas9 gene editing into every subdiscipline of biomedical research requires concomitant training of qualified technicians. The Technician Training in Gene Editing (TTiGE) project addresses this need through a collaboration between instructors at Delaware Technical Community College (DTCC) and scientists at the Gene Editing Institute (GEI). Through this partnership, the latest techniques and applications of gene editing being used in the research settings of GEI will be integrated into student-centered curriculum in several courses in the DTCC Biotechnology program. These activities will then be disseminated nationally to community college instructors through workshops with instruction in gene editing techniques. Training will also be provided in using high impact instruction in the classroom which has been proven to have significant impact on retention in STEM programs. By training instructors, the number of students receiving training in CRISPR gene editing techniques has the potential to support the increase use of gene editing in bioscience companies and research laboratories throughout the nation.The goal of the TTiGE project is to increase the number of biotechnology technicians knowledgeable in CRISPR/Cas9 gene editing and associated skills. A GEI technician will be supported to transfer gene editing technical knowledge and advances to DTCC faculty who will create high impact curriculum to be incorporated into several classes in the Biotechnology program. This program further enhances the Biotechnology program which was strengthened by incorporation of active learning and undergraduate research (Award # 1003649). Two and five-day workshops will be developed to train community college faculty in gene editing techniques in yeast and mammalian cells and the use of student-centered curriculum. Follow-up communication will provide workshop attendees with technical and educational support and disseminate the latest technical advancements in the field. Project evaluation will measure the impact on Delaware Tech students and track incorporation of the materials into courses by workshop attendees. The teacher training in student-centered pedagogy will build teacher confidence to expand these practices into other courses with the goal of increasing retention and graduation rates of bioscience students. The gene editing focus of the TTiGE project insures that technicians are graduating with critical entry-level skills enriched with employability skills.