Technician Training in Gene Editing

基因编辑技术人员培训

• 批准号: 1700660
• 负责人: John McDowell
• 金额: $ 89.53万
• 依托单位: Delaware Technical & Community College Stanton-Newark Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1700660&HistoricalAwards=false
• 关键词: Technician; Training; Gene; Editing

The rapid expansion of CRISPR/Cas9 gene editing into every subdiscipline of biomedical research requires concomitant training of qualified technicians. The Technician Training in Gene Editing (TTiGE) project addresses this need through a collaboration between instructors at Delaware Technical Community College (DTCC) and scientists at the Gene Editing Institute (GEI). Through this partnership, the latest techniques and applications of gene editing being used in the research settings of GEI will be integrated into student-centered curriculum in several courses in the DTCC Biotechnology program. These activities will then be disseminated nationally to community college instructors through workshops with instruction in gene editing techniques. Training will also be provided in using high impact instruction in the classroom which has been proven to have significant impact on retention in STEM programs. By training instructors, the number of students receiving training in CRISPR gene editing techniques has the potential to support the increase use of gene editing in bioscience companies and research laboratories throughout the nation.The goal of the TTiGE project is to increase the number of biotechnology technicians knowledgeable in CRISPR/Cas9 gene editing and associated skills. A GEI technician will be supported to transfer gene editing technical knowledge and advances to DTCC faculty who will create high impact curriculum to be incorporated into several classes in the Biotechnology program. This program further enhances the Biotechnology program which was strengthened by incorporation of active learning and undergraduate research (Award # 1003649). Two and five-day workshops will be developed to train community college faculty in gene editing techniques in yeast and mammalian cells and the use of student-centered curriculum. Follow-up communication will provide workshop attendees with technical and educational support and disseminate the latest technical advancements in the field. Project evaluation will measure the impact on Delaware Tech students and track incorporation of the materials into courses by workshop attendees. The teacher training in student-centered pedagogy will build teacher confidence to expand these practices into other courses with the goal of increasing retention and graduation rates of bioscience students. The gene editing focus of the TTiGE project insures that technicians are graduating with critical entry-level skills enriched with employability skills.

CRISPR/Cas9基因编辑迅速扩展到生物医学研究的每个分支学科，需要相应的合格技术人员培训。基因编辑技术人员培训（TTiGE）项目通过特拉华技术社区学院（DTCC）的教师和基因编辑研究所（GEI）的科学家之间的合作解决了这一需求。通过这种伙伴关系，GEI研究环境中使用的最新基因编辑技术和应用将被整合到DTCC生物技术项目的几门课程中，以学生为中心。然后，这些活动将通过提供基因编辑技术指导的讲习班在全国范围内传播给社区大学教师。还将提供在课堂上使用高影响力教学的培训，这已被证明对STEM项目的保留率有重大影响。通过培训教师，接受CRISPR基因编辑技术培训的学生人数有可能支持全国生物科学公司和研究实验室增加基因编辑的使用。TTiGE项目的目标是增加了解CRISPR/Cas9基因编辑和相关技能的生物技术人员的数量。将支持GEI技术人员将基因编辑技术知识和进步传授给DTCC教师，后者将创建高影响力的课程，并将其纳入生物技术项目的几个课程中。该计划进一步加强了生物技术计划，该计划通过纳入主动学习和本科生研究而得到加强（奖励# 1003649）。将举办为期两天和五天的讲习班，培训社区学院的教师掌握酵母和哺乳动物细胞的基因编辑技术，以及如何使用以学生为中心的课程。后续沟通将为讲习班与会者提供技术和教育支持，并传播该领域的最新技术进展。项目评估将衡量对特拉华理工学院学生的影响，并跟踪研讨会参与者将材料纳入课程的情况。教师在以学生为中心的教学法方面的培训将建立教师的信心，将这些实践扩展到其他课程，目标是提高生物科学学生的保留率和毕业率。TTiGE项目的基因编辑重点确保技术人员毕业时具备关键的入门技能和丰富的就业技能。