Acquisition of a 400 MHz NMR for Research and Training at Grand Valley State University, Grand Rapids Community College and Aquinas College

采购 400 MHz NMR 用于大谷州立大学、大急流城社区学院和阿奎那学院的研究和培训

• 批准号: 1725699
• 负责人: Shannon Biros
• 金额: $ 29万
• 依托单位: Grand Valley State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2020-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1725699&HistoricalAwards=false
• 关键词: Acquisition; 400; MHz; NMR; Research

This award is supported by the Major Research Instrumentation Program (MRI) and the Chemistry Research Instrumentation Program. With it, Professor Shannon Biros from Grand Valley State University and colleagues have acquired a 400 MHz nuclear magnetic resonance (NMR) spectrometer. An NMR spectrometer enables the identification of the atoms (for example, hydrogen, carbon, etc.) in the material. This analytic technique is used to identify chemicals, drugs, proteins or unknown substances. The spectrometer is housed at Grand Valley State University (GVSU) and used by their faculty and students, as well as faculty and students at Grand Rapids Community College (GRCC) and Aquinas College. The instrument advances research on metals important for potential uses in optical materials and biosensors, on protein binding to antibiotic substances and on new materials with applications such as photovoltaics and solar cells. Many students at GVSU and GRCC (40-60%) are the first in their family to attend college. The exposure of these students to cutting edge instrumentation facilitates their development as scientifically literate individuals and contributes to a competitive scientific workforce.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts investigations of selective f-element extraction agents; studies of bond fission regioselectivity in nucleophilic aromatic substitution of arylsulfonates, the preparations of main group derivatives, and d,f-block metallation of mono- and diphosphines. The instrument also serves researchers investigating the structure lactamase enzymes and studying the relationship between ligand/additive structure and reactivity.

该奖项由主要研究仪器计划（MRI）和化学研究仪器计划支持。有了它，来自大峡谷州立大学的Shannon Biros教授和同事们获得了一台400 MHz的核磁共振（NMR）光谱仪。NMR光谱仪能够识别原子（例如，氢、碳等）。材料中。这种分析技术用于识别化学物质、药物、蛋白质或未知物质。光谱仪位于大峡谷州立大学（GVSU），由他们的教师和学生以及大急流城社区学院（GRCC）和阿奎那学院的教师和学生使用。 该仪器推动了对光学材料和生物传感器潜在用途重要的金属、与抗生素物质结合的蛋白质以及具有光致发光和太阳能电池等应用的新材料的研究。GVSU和GRCC的许多学生（40-60%）是家庭中第一个上大学的学生。 这些学生接触尖端仪器有助于他们发展成为具有科学素养的个人，并有助于培养一支具有竞争力的科学队伍。NMR光谱仪的奖项旨在加强各级的研究和教育。特别是对选择性氟元素萃取剂的研究、芳基磺酸盐的亲核芳族取代中键裂区域选择性的研究、主族衍生物的制备以及单膦和双膦的d，f-嵌段甲基化的研究。该仪器还可用于研究内酰胺酶的结构以及研究配体/添加剂结构与反应性之间的关系。

项目成果

Synthesis and crystallographic characterization of N-allyl-N-benzyl-4-methylbenzenesulfonamide

N-烯丙基-N-苄基-4-甲基苯磺酰胺的合成及晶体学表征

• DOI: 10.5155/eurjchem.11.3.245-249.2017
• 发表时间: 2020
• 期刊: European Journal of Chemistry
• 作者: Stenfors, Brock Anton;Ngassa, Felix Nyuangem
• 通讯作者: Ngassa, Felix Nyuangem

Crystal structure of 4-methyl- N -propylbenzenesulfonamide

4-甲基-N-丙基苯磺酰胺的晶体结构

• DOI: 10.1107/s2056989020007756
• 发表时间: 2020
• 期刊: Acta Crystallographica Section E Crystallographic Communications
• 作者: Stenfors, Brock A.;Collins, Rachel C.;Duran, Jonah R.;Staples, Richard J.;Biros, Shannon M.;Ngassa, Felix N.
• 通讯作者: Ngassa, Felix N.

Crystal structures of two bis-carbamoylmethylphosphine oxide (CMPO) compounds

两种双氨基甲酰基甲基氧化膦 (CMPO) 化合物的晶体结构

• DOI: 10.1107/s205698901900820x
• 发表时间: 2019
• 期刊: Acta Crystallographica Section E Crystallographic Communications
• 作者: VanderWeide, Andrew I.;Staples, Richard J.;Biros, Shannon M.
• 通讯作者: Biros, Shannon M.

Crystal structure of 1-[(4-methylbenzene)sulfonyl]pyrrolidine

1-[(4-甲基苯)磺酰基]吡咯烷的晶体结构

• DOI: 10.1107/s205698902000208x
• 发表时间: 2020
• 期刊: Acta Crystallographica Section E Crystallographic Communications
• 作者: Stenfors, Brock A.;Staples, Richard J.;Biros, Shannon M.;Ngassa, Felix N.
• 通讯作者: Ngassa, Felix N.

Syntheses and crystal structures of the anhydride 4-oxatetracyclo[5.3.2.0 2,6 .0 8,10 ]dodec-11-ene-3,5-dione and the related imide 4-(4-bromophenyl)-4-azatetracyclo[5.3.2.0 2,6 .0 8,10 ]dodec-11-ene-3,5-dione

酸酐 4-oxatetracyclo[5.3.2.0 2,6 .0 8,10 ]dodec-11-ene-3,5-dione 和相关酰亚胺 4-(4-bromoryl)-4-azatetracyclo[ 的合成和晶体结构]

• DOI: 10.1107/s2056989020009512
• 发表时间: 2020
• 期刊: Acta Crystallographica Section E Crystallographic Communications
• 作者: Hulsman, Andrew;Lorenzana, Isabel;Schultz, Theodore;Squires, Breezy;Stenfors, Brock A.;Tolonen, Mason;Staples, Richard J.;Biros, Shannon M.;Winchester, William R.
• 通讯作者: Winchester, William R.