MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance Console Upgrade for Chemical and Materials Science Research

MRI：为化学和材料科学研究购买 400 MHz 核磁共振控制台升级版

• 批准号: 1726173
• 负责人: Aaron Sadow
• 金额: $ 28.65万
• 依托单位: Iowa State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2020-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1726173&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; Nuclear

This award is supported by the Major Research Instrumentation (MRI) and the Chemistry Research Instrumentation (CRIF) pPograms. Professor Aaron Sadow from Iowa State University and colleagues Yan Zhao, Levi Stanley, Martin Thuo and Sarah Cady have acquired an upgrade for a 400 MHz nuclear magnetic resonance (NMR) spectrometer by equipping it with a new console and a liquid-nitrogen, cooled cryoprobe as well as a flow NMR system to monitor kinetics. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as the study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists to study the structure of molecules. It is used to identify unknown substances, to understand the specific arrangements of atoms within molecules, and to study the changes of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is important to chemists who are carrying out frontier research. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework as well as researchers and graduate students and high school students who participate in outreach activities. The NMR center also offers data collection and analysis for nearby industries.This NMR spectrometer enhances research and education at all levels. It especially benefits the development of synthetic materials to produce bacterial biofilms and studies of catalytic reaction pathways. The spectrometer is also used in developing catalysts for new reactions that couple carbon-hydrogen and carbon-halogen bond activation with carbon-carbon and carbon-heteroatom bond formation and for engineering soft materials, one bond at a time.

这一奖项得到了主要研究仪器(MRI)和化学研究仪器(CRIF)的支持。爱荷华州立大学的Aaron Sadow教授及其同事赵燕、Levi Stanley、Martin Thuo和Sarah Cady对400 MHz核磁共振(核磁共振)光谱仪进行了升级，为其配备了一个新的控制台、一个液氮冷却的低温探头以及一个用于监测动力学的流动核磁共振系统。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及对生物相关物种的研究。总体而言，核磁共振波谱是化学家研究分子结构的最强大的工具之一。它被用来识别未知物质，了解分子内原子的具体排列，并研究分子在溶液或固体状态下相互作用的变化。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是很重要的。这些核磁共振研究的结果对合成有机/无机化学、材料化学、法医学和生物化学产生了影响。该仪器是本科生通过独立的学生研究和传统的学术课程进行的教学和研究的组成部分，也是参加外联活动的研究人员、研究生和高中生的组成部分。核磁共振中心还为附近的工业提供数据收集和分析。这台核磁共振光谱仪加强了各级研究和教育。尤其有利于细菌生物膜合成材料的开发和催化反应途径的研究。该光谱仪还用于开发新反应的催化剂，这些反应将碳-氢和碳-卤键的活化与碳-碳和碳-杂原子键的形成结合起来，并用于工程软材料，一次一个键。