Roll-Imprint Manufacturing of Three-Dimensional Nanomagnetic Arrays

三维纳米磁性阵列的滚压印制造

• 批准号: 1762884
• 负责人: Bethanie Stadler
• 金额: $ 43.32万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1762884&HistoricalAwards=false
• 关键词: Roll; Imprint; Manufacturing; Three; Dimensional

This grant promotes the progress of science by exploring the fundamental design principles behind the roll-imprint process for manufacturing nanomagnetic arrays for a wide range of applications, including individualized nanomedicine and radar thus advancing national health, prosperity and security. Current nanomedicine uses magnetic iron oxide nanoparticles in bio-labels for cancer diagnosis and therapy and for magnetic resonance imaging (MRI). Magnetic thin films are promising in circulators that block reflections from re-entering radar sources, hence eliminating noise and enhancing performance. This project disrupts both of these diverse technologies using three dimensional (3D) nanomagnetic arrays. The arrays are essentially groupings of barcoded nanowires that can be visualized as the pelt of a porcupine - shrunk to fit on the tip of a pen. Individually, the 'quills' are so small that they are internalized by cells, leading to effective cellular barcoding. As an array, or 'pelt', the quill or nanowire assembly acts like a one-way mirror for radar signals. The manufacturing process developed here enables rolls of 3D nanomagnetic arrays to be produced with a yield of one billion nanowires per minute. Undergraduate and graduate student training by two female electrical engineers supports education and diversity and enables students to conduct research in medical diagnosis and radar for self-driving cars for the benefit of society.Fundamental design principles are established for roll-imprint manufacturing of three dimensional (3D) nanomagnetic arrays, including nanostructure design, process design, and quality control design. Two underlying testbeds, radio-frequency identification (RFID) bio-labels and high frequency circulators for self-driving cars, are used to verify the designs. For nanostructure design, hierarchical nanostructures are composed of zero dimensional (0D) nanodisks stacked into one-dimensional (1D) nanowires that are inside two-dimensional (2D) arrays of columnar nanopores to make three-dimensional (3D) structures. The magnetic spin structures are simulated to facilitate design with experimental verification. The process design involves roll-imprinting of aluminum before anodization to produce aluminum oxide templates containing columnar nanopores with long range order. Electrodeposition is then used to fill these nanopores with single component ferromagnetic metals and multilayers according to the desired nanostructure designs. Quality control design involves high frequency circuits, including coplanar waveguides to measure ferromagnetic resonance and custom designed circulators to measure composite properties. Importantly, the quality control design is directly applicable for testbed success. Previous work has successfully demonstrated 3D nanomagnetic arrays that were synthesized using planar components with areas of square-centimeter. This work scales up manufacturing to square-meter per hour rates in a step-continuous roll-to-roll process.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这笔赠款通过探索用于制造纳米磁性阵列的滚印工艺背后的基本设计原理来促进科学进步，该阵列具有广泛的应用，包括个性化纳米医学和雷达，从而促进国家健康、繁荣和安全。目前的纳米医学在生物标记中使用磁性氧化铁纳米粒子，用于癌症诊断和治疗以及磁共振成像 (MRI)。磁性薄膜在循环器中很有前景，它可以阻挡重新进入雷达源的反射，从而消除噪声并提高性能。该项目使用三维 (3D) 纳米磁性阵列颠覆了这两种不同的技术。这些阵列本质上是条形码纳米线的分组，可以将其可视化为豪猪的毛皮——缩小以适合笔尖。单独而言，“羽毛管”非常小，可以被细胞内化，从而产生有效的细胞条形码。作为一个阵列或“毛皮”，羽毛管或纳米线组件的作用就像雷达信号的单向镜子。这里开发的制造工艺能够以每分钟 10 亿根纳米线的产量生产 3D 纳米磁性阵列卷。由两名女性电气工程师进行的本科生和研究生培训支持教育和多样性，使学生能够开展医学诊断和自动驾驶汽车雷达方面的研究，造福社会。为三维（3D）纳米磁性阵列的滚压印制造建立了基本设计原则，包括纳米结构设计、工艺设计和质量控制设计。两个底层测试平台：射频识别 (RFID) 生物标签和自动驾驶汽车的高频循环器，用于验证设计。对于纳米结构设计，分层纳米结构由堆叠成一维 (1D) 纳米线的零维 (0D) 纳米盘组成，一维 (1D) 纳米线位于柱状纳米孔的二维 (2D) 阵列内，形成三维 (3D) 结构。对磁自旋结构进行了模拟，以方便设计和实验验证。该工艺设计包括在阳极氧化之前对铝进行辊压印，以生产含有长程有序柱状纳米孔的氧化铝模板。然后根据所需的纳米结构设计，使用电沉积方法用单组分铁磁金属和多层填充这些纳米孔。 质量控制设计涉及高频电路，包括用于测量铁磁共振的共面波导和用于测量复合材料特性的定制设计循环器。重要的是，质量控制设计直接适用于测试台的成功。先前的工作已成功演示了使用面积为平方厘米的平面组件合成的 3D 纳米磁性阵列。这项工作通过逐步连续的卷对卷工艺将制造规模扩大到每小时平方米的速度。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力优点和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

A Ferromagnetic Resonance Measurement System for Small Volume Magnetic Nanowires

小体积磁纳米线的铁磁共振测量系统

• DOI: 10.1109/apusncursinrsm.2019.8889110
• 发表时间: 2019
• 期刊: IEEE APS/URSI
• 作者: Zhang, Yali;Um, Joseph;Stadler, Bethanie;Franklin, Rhonda
• 通讯作者: Franklin, Rhonda

Bioapplications of Magnetic Nanowires: Barcodes, Biocomposites, Heaters

• DOI: 10.1109/tmag.2022.3151608
• 发表时间: 2022-08-01
• 期刊: IEEE TRANSACTIONS ON MAGNETICS
• 影响因子: 2.1
• 作者: Kouhpanji，Mohammad Reza Zamani;Zhang，Yali;Stadler，Bethanie J. H.
• 通讯作者: Stadler，Bethanie J. H.

Magnetic Nanowires for RF applications: Ferromagnetic Resonance and Permeability Characterization

• DOI: 10.1109/mwsym.2019.8700826
• 发表时间: 2019-06
• 期刊: 2019 IEEE MTT-S International Microwave Symposium (IMS)
• 作者: Yali Zhang;J. Um;Wen-ming Zhou;B. Stadler;Rhonda R. Franklin

Signal Enhancement for Ferromagnetic Resonance Measurement of Magnetic Nanowire array

磁性纳米线阵列铁磁共振测量的信号增强

• DOI: 10.1109/apusncursinrsm.2019.8889102
• 发表时间: 2019
• 期刊: APS
• 作者: Zhang, Yali;Um, Joseph;Stadler, Bethanie;Franklin, Rhonda
• 通讯作者: Franklin, Rhonda

Realizing the Principles for Remote and Selective Detection of Cancer Cells Using Magnetic Nanowires

实现利用磁性纳米线远程选择性检测癌细胞的原理

• DOI: 10.1021/acs.jpcb.1c04394
• 发表时间: 2021
• 期刊: The Journal of Physical Chemistry B
• 作者: Zamani Kouhpanji, Mohammad Reza;Nemati, Zohreh;Modiano, Jaime;Franklin, Rhonda;Stadler, Bethanie
• 通讯作者: Stadler, Bethanie