I-Corps: Fluorescent Dyes and Pigments by Small Molecule Isolation Lattices, SMILES

I-Corps：小分子隔离晶格的荧光染料和颜料，SMILES

• 批准号: 1826693
• 负责人: Amar Flood
• 金额: $ 5万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2019-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1826693&HistoricalAwards=false
• 关键词: Corps; Fluorescent; Dyes; Pigments; Small

The broader impact/commercial potential of this I-Corps project is related to the development of fluorescent materials. Commercial potential is expected to emerge when replacing costly existing technologies (like quantum dots) with inexpensive materials able that can be embodied as highly fluorescent organic solids. Such materials are expected to create new value and have commercial potential in several markets in which either aesthetics, brightness, or color transmission is critical for performance. Our primary markets of interest are colorants in paints and polymers. Fluorescent brighteners represent an important segment of the global dyes and pigments market (a $30B per year industry). We believe our technology can expand this segment by streamlining the formulation and processing of fluorescent materials, and by broadening the available color palate. Immediate applications would arise in creation of new fluorescent paints and coatings for construction and safety applications, and may also provide new user-friendly color options to the growing market for 3D printing materials. We anticipate additional downstream applications to arise in customized biolabeling technologies and solar power generation. If successful, the broader impacts also include the training of scientists in the process of commercialization. This I-Corps project provides a universal tool to address the outstanding intellectual challenge of understanding how to reverse loss of fluorescence from solid-state formulations of organic dyes. The intellectual merits will derive from new synthetic preparations of fluorescent dye and pigment technology by a method called small molecule isolation lattices, or SMILES. This project derives from research that has provided a way to insulate the color-carrying dye molecules from one another allowing their fluorescence to be rescued. A wide range of proof-of-principle experiments shows how to prepare the SMILES materials simply by mixing a proprietary compound with existing fluorescent compounds. The results show fluorescence in solids, as films, crystals, dyes, and particles under identical conditions that render conventional fluorescent dyes non-emissive.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛的影响/商业潜力与荧光材料的开发有关。在用廉价的材料替换昂贵的现有技术（例如量子点）时，商业潜力将出现，这些材料可以体现为高度荧光的有机固体。预计此类材料将在美学，亮度或颜色传输对性能至关重要的几个市场中具有新价值，并具有商业潜力。我们感兴趣的主要市场是油漆和聚合物中的着色剂。荧光照亮器代表了全球染料和颜料市场的重要部分（每年$ 30B）。我们认为，我们的技术可以通过简化荧光材料的配方和处理以及扩大可用的色泽来扩展这一细分市场。将立即应用于为建筑和安全应用创建新的荧光涂料和涂料，还可能为增长的3D打印材料的市场提供新的用户友好颜色选择。我们预计在定制的生物标记技术和太阳能发电中会出现其他下游应用程序。如果成功，更广泛的影响还包括在商业化过程中对科学家的培训。这个I-Corps项目提供了一种通用工具，可以解决如何从有机染料的固态配方中扭转荧光损失的杰出知识挑战。智力优点将通过一种称为小分子隔离晶格或微笑的方法源自荧光染料和色素技术的新合成制剂。该项目源于研究，该研究提供了一种将赋予颜色的染料分子隔开的方法，从而可以挽救它们的荧光。广泛的原则证明实验显示了如何仅通过将专有化合物与现有荧光化合物混合而准备微笑材料。结果表明，固体的荧光，膜，晶体，染料和颗粒在相同的条件下导致常规荧光染料非复杂性。该奖项反映了NSF的法定任务，并被认为是通过基金会的智力优点和更广泛影响的审查标准通过评估来通过评估来支持的。