EAGER: Collaborative: Secure and Trustworthy Cyberphysical Microfluidic Systems

EAGER：协作：安全且值得信赖的网络物理微流体系统

• 批准号: 1833624
• 负责人: Ramesh Karri
• 金额: $ 8万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1833624&HistoricalAwards=false
• 关键词: EAGER; Collaborative; Secure; Trustworthy; Cyberphysical

This project's overarching goal is to ensure the security and trustworthiness of cyber-physical microfluidic systems (CPMS). Microfluidic systems are devices that handle small volumes of fluids and are usually coupled with "cyber" elements such as sensors and intelligent control algorithms to improve performance and reliability. CPMS are coming of age in an era of rampant cybersecurity issues, and novel security and trust solutions are the need of the hour. Secure and trustworthy CPMS will be realized through three central research tasks: 1) analyzing security threats, motivations, attack surfaces, and their consequences for the research landscape, industry, and society; 2) developing novel architectures, protocols, hardware, and algorithms to prevent, detect, and mitigate these threats; and 3) experiments on the benchtop to validate the developed approaches and to expose subtle issues that arise at the biochemical level. Miniaturized, low-cost CPMS that are also secure and trustworthy will be revolutionary. In academia, this project will foster multi-disciplinary research and education for students of hardware design, computer-aided design, molecular biology, and security. In industry, growth and investment will be fostered by protecting intellectual property and providing an impetus for adoption by end users. For society, CPMS designed with security in mind should help in establishing trust. The data collected in this research will be disseminated through publications and public portals, such as GitHub and https://sites.google.com/a/tamu.edu/security-of-microfluidic-biochips/.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该项目的总体目标是确保网络物理微流控系统（CPMS）的安全性和可信度。微流体系统是处理小体积流体的装置，并且通常与诸如传感器和智能控制算法的“网络”元件耦合以提高性能和可靠性。CPMS是在网络安全问题猖獗的时代发展起来的，新的安全和信任解决方案是时代的需要。 安全和可信的CPMS将通过三个中心研究任务来实现：1）分析安全威胁，动机，攻击面及其对研究环境，行业和社会的影响; 2）开发新的架构，协议，硬件和算法来预防，检测和减轻这些威胁;以及3）在实验台上进行实验，以验证所开发的方法，并揭示在生物化学水平上出现的微妙问题。 小型化、低成本、安全可靠的CPMS将是革命性的。在学术界，该项目将促进硬件设计，计算机辅助设计，分子生物学和安全学生的多学科研究和教育。在工业方面，将通过保护知识产权和推动最终用户采用知识产权来促进增长和投资。对于社会来说，考虑到安全性而设计的CPMS应该有助于建立信任。本研究中收集的数据将通过出版物和公共门户网站（如GitHub和https://sites.google.com/a/tamu.edu/security-of-microfluidic-biochips/.This奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。

项目成果

Programmable Daisychaining of Microelectrodes to Secure Bioassay IP in MEDA Biochips

• DOI: 10.1109/tvlsi.2020.2967029
• 发表时间: 2020-02
• 期刊: IEEE Transactions on Very Large Scale Integration (VLSI) Systems
• 影响因子: 2.8
• 作者: Tung-Che Liang;K. Chakrabarty;R. Karri

Bio-chemical Assay Locking to Thwart Bio-IP Theft

• DOI: 10.1145/3365579
• 发表时间: 2019-11
• 期刊: ACM Transactions on Design Automation of Electronic Systems (TODAES)
• 作者: Sukanta Bhattacharjee;Jack Tang;Sudip Poddar;Mohamed Ibrahim;R. Karri;K. Chakrabarty

Secure Assay Execution on MEDA Biochips to Thwart Attacks Using Real-Time Sensing

使用实时传感在 MEDA 生物芯片上安全执行检测以阻止攻击

• DOI: 10.1145/3374213
• 发表时间: 2020
• 期刊: ACM Transactions on Design Automation of Electronic Systems
• 影响因子: 1.4
• 作者: Liang, Tung-Che;Shayan, Mohammed;Chakrabarty, Krishnendu;Karri, Ramesh
• 通讯作者: Karri, Ramesh

Towards Secure Checkpointing for Micro-Electrode-Dot-Array Biochips

实现微电极点阵列生物芯片的安全检查点

• DOI: 10.1109/tcad.2020.2979972
• 发表时间: 2020
• 期刊: IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
• 影响因子: 2.9
• 作者: Shayan, Mohammed;Liang, Tung-Che;Bhattacharjee, Sukanta;Chakrabarty, Krishnendu;Karri, Ramesh
• 通讯作者: Karri, Ramesh

Synthesis of Tamper-Resistant Pin-Constrained Digital Microfluidic Biochips

• DOI: 10.1109/tcad.2018.2883901
• 发表时间: 2020-01
• 期刊: IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
• 影响因子: 2.9
• 作者: Jack Tang;Mohamed Ibrahim;K. Chakrabarty;R. Karri