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Meeting: Stress phenotype: linking molecular, cellular and physiological stress (Society of Integrative and Comparative Biology Symposium, January 5, 2019 in Tampa, FL).

会议：应激表型：连接分子、细胞和生理应激（综合与比较生物学研讨会，2019 年 1 月 5 日在佛罗里达州坦帕）。

基本信息

批准号：
1840903
负责人：
Britt Heidinger
金额：
$ 1.59万
依托单位：
North Dakota State University Fargo
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-15 至 2019-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1840903&HistoricalAwards=false
关键词：
Meeting Stress phenotype linking molecular

项目摘要

Most organisms respond to environmental and social stressors by a stress response. However, knowledge of how the stress response is integrated across levels of organization from molecules, to cells, to the whole organism remains limited. This symposium will bring together biologists across levels of organization and at different career stages to gain a richer insight into how organisms respond to stress. During the symposium, speakers from different levels of organization will alternate with one another. Immediately following the symposium, a structured round table discussion will be hosted aimed at identifying key outstanding questions in stress biology and integrative approaches that can be used to study the stress responses of animals, including domesticated and rare species, across levels of organization. There will also be complimentary oral and poster sessions geared towards early career scientists from diverse backgrounds to increase the potential for idea exchange and collaborations between scientists at different career stages and that traditionally study the stress response at different levels of analyses.Most organisms initiate a highly conserved stress response in the face of environmental and social stressors. Yet, information about how the stress response is integrated across levels of biological organization from genomes to phenomes is incomplete. However, it is becoming increasingly clear that a comprehensive understanding of the evolution of the stress response will require integrative studies that span levels of analyses. This information will be critical for predicting how selection will influence the expression of this complex phenotype at the organismal level, as well as how the integration of the underlying mechanisms will influence the evolutionary response to selection. As diverse organisms are expected to experience rising stress exposure in the face of anthropogenic disturbance and rapidly changing environments, this knowledge is becoming increasingly urgent.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

大多数生物体对环境和社会应激源的反应是应激反应。然而，从分子到细胞，再到整个生物体，关于应激反应是如何跨组织水平整合的知识仍然有限。这次研讨会将把处于不同组织水平和不同职业阶段的生物学家聚集在一起，以更深入地了解有机体如何应对压力。在研讨会期间，来自不同组织级别的发言者将轮流发言。研讨会结束后，将立即主办一次有组织的圆桌讨论会，旨在确定应激生物学中的关键悬而未决的问题，以及可用于研究动物(包括驯养和稀有物种)跨组织级别的应激反应的综合方法。还将有针对来自不同背景的早期职业科学家的免费口头和海报会议，以增加不同职业阶段科学家之间思想交流和合作的可能性，这些科学家传统上在不同的分析水平上研究压力反应。大多数生物体在面对环境和社会压力时会启动高度保守的压力反应。然而，关于压力反应是如何在从基因组到物候组的生物组织水平上整合的信息还不完整。然而，越来越清楚的是，要全面了解应激反应的演变，需要进行跨分析水平的综合研究。这些信息对于预测选择将如何影响这种复杂表型在生物水平上的表达，以及潜在机制的整合将如何影响对选择的进化反应将是至关重要的。由于各种生物在面对人为干扰和快速变化的环境时预计会经历越来越多的压力暴露，这一知识变得越来越迫切。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。