Structuring of magnetic particle doped biopolymers by magnetica

通过Magnetica构建磁性颗粒掺杂生物聚合物

• 批准号: 238064286
• 负责人: Professor Dr. Thomas Heinze
• 金额: --
• 依托单位: Leibniz-Institut für Photonische Technologien (IPHT)
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2013
• 资助国家: 德国
• 起止时间: 2012-12-31 至 2017-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/238064286?language=en
• 关键词: Structuring; magnetic; particle; doped; biopolymers

Aim of the project is remote control of the properties of biocompatible hybrid materials consisting of meltable biopolymers (especially dextran esters) and magnetic nanoparticles by means of interaction between matrix and particles using magnetic fields. It will be investigated how a local enrichment of particles and a structural i.e. magnetic anisotropy, respectively, can be generated. By such an anisotropy or particle enrichment near the surface surface properties can be influenced in dependence on the structure of the dextran ester. That leads to macroscopical properties relevant for applications, like the specific absorption rate (heating behavior in an AC-magnetic field), roughness, wettability etc. Moreover It will be investigated if a reorientation of matrix material (phase separation, crystallization) takes place or can be induced. The composite samples will be characterized by optical and Raman spectroscopy, electron microscopy, magnetic methods and measurement of the surface energy. In case of a successful implementation of the concept a treatment of biofilms or cells is possible.

该项目的目的是通过利用磁场使基质和颗粒相互作用，远程控制由可熔融生物聚合物(特别是葡聚糖酯)和磁性纳米颗粒组成的生物兼容杂化材料的性能。将研究如何分别产生颗粒的局部富集性和结构性即磁各向异性。通过这种各向异性或表面附近颗粒的富集性，可以根据葡聚糖酯的结构来影响其性质。这导致了与应用相关的宏观性质，如比吸收率(在交流磁场中的加热行为)、粗糙度、润湿性等。此外，将研究是否发生或能够诱导基质材料的重取向(相分离、结晶)。用光学和拉曼光谱、电子显微镜、磁学方法和表面能测量对复合样品进行了表征。在成功实施这一概念的情况下，生物膜或细胞的治疗是可能的。