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MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer for Undergraduate Research and Training

MRI：采购 400 MHz 核磁共振 (NMR) 波谱仪用于本科生研究和培训

基本信息

批准号：
1917696
负责人：
Nikolaus Loening
金额：
$ 38.24万
依托单位：
Lewis and Clark College
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-01 至 2022-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1917696&HistoricalAwards=false
关键词：
MRI Acquisition 400 MHz Nuclear

项目摘要

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Nikolaus Loening from Lewis and Clark College and colleagues Louis Kuo and Casey Jones are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students during the summer research period, in independent study projects during the academic year and as part of final-year undergraduate thesis projects. Collaborations with researchers at Linfield College, Pacific University and high schools are in place. The award is aimed at enhancing research and education at all levels. It is especially helpful in studies of how organometallic complexes are used to degrade pesticides and to desulfurize fossil fuels to make them more environmentally friendly as well as for developing and characterizing how compounds such as resveratrol are released from metals which may be relevant for stent design. The spectrometer is also useful for developing surface-supported catalysts for organic synthesis, and for characterizing the structures of venom peptides.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学仪器项目支持。刘易斯和克拉克学院的Nikolaus Loening教授及其同事Louis Kuo和Casey Jones正在获得一台400兆赫的核磁共振（NMR）光谱仪。总的来说，核磁共振波谱学是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液或固体状态下分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。核磁共振的研究提高了对合成有机/无机化学，材料化学和生物化学的理解。该仪器是本科生在夏季研究期间、在学年的独立研究项目中以及在最后一年的本科论文项目中进行的教学和研究的组成部分。与林菲尔德学院、太平洋大学和高中的研究人员合作。该奖项旨在加强各级的研究和教育。这在研究有机金属配合物如何用于降解农药和脱硫化石燃料以使其更加环保以及开发和表征诸如白藜芦醇之类的化合物如何从金属中释放可能与支架设计相关的研究中尤其有用。该光谱仪还可用于开发用于有机合成的表面负载催化剂，并用于表征毒液肽的结构。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。