MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer for Undergraduate Research and Training

该奖项由主要研究仪器和化学仪器项目支持。刘易斯和克拉克学院的尼古拉斯·勒宁教授及其同事路易斯·郭和凯西·琼斯正在获取一台400兆赫的核磁共振(核磁共振)光谱仪。总体而言，核磁共振波谱是化学家用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。核磁共振研究提高了对合成有机/无机化学、材料化学和生物化学的理解。该仪器是本科生在暑期研究期间进行的教学和研究中不可或缺的一部分，也是本学年独立研究项目和最后一年本科论文项目的一部分。与林菲尔德学院、太平洋大学和高中的研究人员合作已经到位。该奖项旨在加强各级的研究和教育。它特别有助于研究有机金属络合物如何用于降解农药和脱硫化石燃料，使其更加环保，以及开发和表征白藜芦醇等化合物是如何从金属中释放出来的，这可能与支架设计相关。该光谱仪还可用于开发用于有机合成的表面支载催化剂，并用于表征毒肽的结构。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Nikolaus Loening from Lewis and Clark College and colleagues Louis Kuo and Casey Jones are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students during the summer research period, in independent study projects during the academic year and as part of final-year undergraduate thesis projects. Collaborations with researchers at Linfield College, Pacific University and high schools are in place. The award is aimed at enhancing research and education at all levels. It is especially helpful in studies of how organometallic complexes are used to degrade pesticides and to desulfurize fossil fuels to make them more environmentally friendly as well as for developing and characterizing how compounds such as resveratrol are released from metals which may be relevant for stent design. The spectrometer is also useful for developing surface-supported catalysts for organic synthesis, and for characterizing the structures of venom peptides.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.