Development of therapeutic agents that target carbonic anhydrase enzymes

开发针对碳酸酐酶的治疗剂

• 批准号: DP0877554
• 负责人: Prof Sally-Ann Poulsen
• 金额: $ 26.08万
• 依托单位: Griffith University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0877554
• 关键词: Development; therapeutic; agents; target; carbonic

This research will discover new chemical entities (compounds) that may lead to therapies for the treatment of cancer, glaucoma and malaria. The research underpins a mechanism to add value to our compounds before partnering with industry to transform the discoveries made here to deliverable therapies that could benefit the health of millions, thus offering a potentially high value contribution to the Australian economy. The experience and commitment of the multi-disciplinary network of researchers offers exceptional training and employment opportunities for tomorrow's scientists in techniques for discovery and characterisation of novel chemicals, and their interaction with disease targets.

这项研究将发现新的化学实体（化合物），可能导致治疗癌症，青光眼和疟疾的疗法。该研究支持一种机制，在与行业合作之前，为我们的化合物增加价值，将这里的发现转化为可交付的疗法，使数百万人的健康受益，从而为澳大利亚经济提供潜在的高价值贡献。多学科研究人员网络的经验和承诺为未来的科学家提供了特殊的培训和就业机会，用于发现和表征新化学品及其与疾病靶点的相互作用。