Chiroptical Sensing and Sorting by Structured Materials and Structured Light

通过结构材料和结构光进行手性光学传感和分类

• 批准号: 1931777
• 负责人: Yongmin Liu
• 金额: $ 38.55万
• 依托单位: Northeastern University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-10-01 至 2024-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1931777&HistoricalAwards=false
• 关键词: Chiroptical; Sensing; Sorting; Structured; Materials

Chiral molecules are asymmetric molecules with left- and right-handed mirror images (called enantiomers) that cannot be superimposed. The principal investigator will use rationally engineered metallic and dielectric nanostructures and structured light beams to substantially enhance sensing and sorting of chiral molecules via an entirely optical approach. This could lead to vastly improved particle and single molecule level detection over current methods. The development of a new class of novel chiral sensors can significantly improve the limit of detection and sorting of biomarkers of diseases and/or single molecules.The proposed development includes, 1) use of chirality of optical fields to synergistically sense and manipulate chiral molecules, 2) fabrication of planar nanostructures using precision lithography techniques to create unique effects, 3) Potential use of nanocubes yielding highly unique sensing capability for sorting of chiral molecules as well as preferentially trapping molecules by chirality and 4) use of nanostructures for the development of ultrasensitive chiroptical spectroscopy using state of the art micro-/nano-manipulation techniques can lead to the development of new class of sensors for molecular sorting. .This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

手性分子是具有不能叠加的左手和右手镜像（称为对映体）的不对称分子。 首席研究员将使用合理设计的金属和介电纳米结构和结构化光束，通过完全光学的方法大大增强手性分子的传感和分选。这可能导致比当前方法大大改进的颗粒和单分子水平检测。开发一类新型手性传感器可以显著提高疾病和/或单个分子的生物标志物的检测和分选的极限。拟议的发展包括：1）利用光场的手性协同感测和操纵手性分子，2）利用精密光刻技术制造平面纳米结构以产生独特的效果，3）纳米立方体的潜在用途，其产生高度独特的感测能力，用于手性分子的分选以及通过手性优先捕获分子，以及4）纳米结构的用途，其用于使用现有技术的微米/纳米光学系统开发超灵敏手性光谱学。操纵技术可以导致开发用于分子分选的新型传感器。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Decoupled Phase Modulation for Circularly Polarized Light via Chiral Metasurfaces

• DOI: 10.1021/acsphotonics.2c01397
• 发表时间: 2022-12
• 期刊: ACS Photonics
• 影响因子: 7
• 作者: Ren-chao Jin;Lin Deng;LiLi Tang;Yue Cao;Yongmin Liu;Z. Dong

Realizing Colorful Holographic Mimicry by Metasurfaces

通过超表面实现彩色全息拟态

• DOI: 10.1002/adma.202005864
• 发表时间: 2021-04-18
• 期刊: ADVANCED MATERIALS
• 影响因子: 29.4
• 作者: Xiong, Bo;Xu, Yihao;Liu, Yongmin
• 通讯作者: Liu, Yongmin

Tunable Optical Forces Enabled by Bilayer van der Waals Materials

• DOI: 10.1002/adom.202301288
• 发表时间: 2023-10
• 期刊: Advanced Optical Materials
• 影响因子: 9
• 作者: Ziqiang Cai;Renchao Jin;Yihao Xu;Yongmin Liu

Software-defined nanophotonic devices and systems empowered by machine learning

• DOI: 10.1016/j.pquantelec.2023.100469
• 发表时间: 2023-04
• 期刊: Progress in Quantum Electronics
• 影响因子: 11.7
• 作者: Yihao Xu;Bo Xiong;Wei Ma;Yongmin Liu

Structured Light Generation Using Angle‐Multiplexed Metasurfaces

• DOI: 10.1002/adom.202300299
• 发表时间: 2023-06
• 期刊: Advanced Optical Materials
• 影响因子: 9
• 作者: Lin Deng;Renchao Jin;Yihao Xu;Yongmin Liu