Collaborative Research: Magnetically Actuated Black Silicon Ratchet Surfaces for Digital Microfluidics
Collaborative Research: Magnetically Actuated Black Silicon Ratchet Surfaces for Digital Microfluidics
批准号:
1951051
负责人:
Sung Cho
金额:
$31.02万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-03-01 至 2024-02-29
中文摘要
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英文摘要
Since most of the sensitive and standardized bio-analytical techniques work in the liquid medium, the lab-on-a-chip system should be able to efficiently handle liquid solutions in micro/nano scale. To date, most of these systems have been developed based on the continuous flow system which lacks device reconfigurability. Consequently, much attention has been drawn to droplet-based lab-on-a-chip systems, namely, digital micro fluidic systems based on electrowetting that manipulate discrete liquid droplets rather than continuous liquid streams. Nevertheless, the electrowetting-based approach suffers from limitations such as high voltage requirement and biofouling, hampering many real applications. This project provides a straightforward pathway to a new digital micro fluidic platform without electrowetting-related limitations. The proposed platform exploits a purely mechanical means to drive discrete liquid droplets in a rapid, flexible, programmable, and reconfigurable manner. This project will also generate information and demonstration materials that can be directly used to promote both classroom teaching and general public's interest in materials, microfluidics, interfacial science, micro/nanotechnology. The project aims to explore the dynamically tunable surface morphology and consequential interfacial wettability using a black silicon ratchet surface in order to seek a new strategy to manipulate liquid droplets for the advancement of digital microfluidics. The proposed ratchet surface involves superhydrophobic black silicon scales on elastomer micropillars such that individual signals actuate individual scales and change the entire surface morphology forming a black silicon ratchet surface that drives liquid droplets. Consequently, droplets are essentially driven mechanically, not electrically. In addition, it is expected that conical nanostructures on the black silicon surface and/or slippery liquid infused porous surfaces to be integrated will significantly reduce biofouling. The proposed approach cannot be realized without elucidating underlying principles and establishing necessary techniques. Two principal investigators’ expertise encompassing mechanics, materials, manufacturing and microfluidics will be combined in order to achieve those understanding and knowledge, and finally open up a new interdisciplinary research area across smart composite materials and digital microfluidics. During the project, three objectives will be systematically pursued to towards the project goal. First, the mechanical characteristics involved in the proposed superhydrophobic ratchet surface will examined, Second, the interaction between liquid droplets and the superhydrophobic ratchet surface will be characterized and associated forces to manipulate liquid droplets on it will be investigated. Finally, droplet manipulations including droplet transporting, merging, and splitting along with the reduced biofouling will be demonstrated.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
Propulsion reversal in oscillating-bubble powered micro swimmer
振荡气泡动力微型游泳器中的推进反转
DOI:
10.1088/1361-6439/ac0e7f
发表时间:
2021
期刊:
Journal of Micromechanics and Microengineering
影响因子:
2.3
作者:
[Liu, Fang-Wei, Zhan, Ye, Cho, Sung Kwon]
通讯作者:
Cho, Sung Kwon
PDMS-Zwitterionic Hybrid for Facile, Antifouling Microfluidic Device Fabrication
PDMS-两性离子杂化物用于简便、防污微流体装置的制造
DOI:
10.1021/acs.langmuir.1c03375
发表时间:
2022
期刊:
Langmuir
影响因子:
3.9
作者:
[Mercader, Anthony, Ye, Sang-Ho, Kim, Seungil, Orizondo, Ryan A., Cho, Sung Kwon, Wagner, William R.]
通讯作者:
Wagner, William R.
STRONG MICROSTREAMING FROM A PINNED OSCILLATING MEMBRANE AND APPLICATION TO GAS EXCHANGE
来自固定振荡膜的强微流及其在气体交换中的应用
DOI:
--
发表时间:
2023
期刊:
2023 IEEE Conference on Microelectromechanical systems
影响因子:
--
作者:
[Anthony L. Mercader, Sung Kwon Cho]
通讯作者:
Sung Kwon Cho
Collaborative Research: Integrated Swimming Microrobots for Intravascular Neuromodulation
-
批准号:2325000
-
项目类别:Standard Grant
-
资助金额:$27.5万
-
财政年份:2023
-
负责人:Sung Cho
-
依托单位:
NRI: 3-D Maneuverable Feedback-Controlled Micro Swimming Drone for Biomedical Applications
-
批准号:1637815
-
项目类别:Standard Grant
-
资助金额:$72.47万
-
财政年份:2016
-
负责人:Sung Cho
-
依托单位:
Collaborative Research: Exploration of Near-Field Thermophotovoltaic Energy Conversion for Efficient Thermal Energy Recycling
-
批准号:1236052
-
项目类别:Standard Grant
-
资助金额:$15.0万
-
财政年份:2012
-
负责人:Sung Cho
-
依托单位:
Microscale Swimming Medibot in Human Body Propelled by Oscillating Bubbles
-
批准号:1029318
-
项目类别:Standard Grant
-
资助金额:$26.78万
-
财政年份:2010
-
负责人:Sung Cho
-
依托单位:
EXP-SA: Collaborative Research: Ultratrace Detection of Explosives Enabled by an Integrated Microfluidic Nanosensing System
-
批准号:0730460
-
项目类别:Standard Grant
-
资助金额:$20.31万
-
财政年份:2008
-
负责人:Sung Cho
-
依托单位:
Collaborative Research: Integrated Microsystem for Ultrasensitive Airborne Pathogen Detection in Real Time
-
批准号:0725525
-
项目类别:Standard Grant
-
资助金额:$16.0万
-
财政年份:2007
-
负责人:Sung Cho
-
依托单位:
Micro Bubble Tweezers for Individual Cell Manipulation and In Vitro Ultrasound Cell Therapy
-
批准号:0601470
-
项目类别:Standard Grant
-
资助金额:$0.0万
-
财政年份:2006
-
负责人:Sung Cho
-
依托单位:
国内基金
海外基金
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