MRI: Acquisition of a 400 MHz NMR spectrometer for undergraduate research and teaching in chemistry

MRI：购买 400 MHz NMR 波谱仪，用于化学本科研究和教学

• 批准号: 2018744
• 负责人: Jeffrey Cannon
• 金额: $ 34万
• 依托单位: Occidental College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2018744&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; NMR

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Occidental College is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with a automatic sample changer to support Professors Jeffrey Cannon, Michael Hill, Andrew Udit, Raul Navarro, Emmanuelle Despagnet-Ayoub and other colleagues. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this college and other nearby institutions. The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts the exploration of synthetic methods for carbon-carbon bond formation and the studies of electrocatalytic carbon-hydrogen bond oxidation at metal-oxo-coated carbon electrodes. The instrumentation is also used for exploring projects varying from energy storage to polymer synthesis. In addition, it benefits investigations of arene dearomatization reactions for natural product synthesis. The spectrometer is also utilized in studies of sulfated ligands displayed on polyvalent bacteriophage for heparin-like anticoagulant activity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划支持。西方学院正在购买一台配备自动换样器的400 MHz核磁共振（NMR）光谱仪，以支持Jeffrey Cannon、Michael Hill、Andrew Udit、Raul Navarro、Emmanuelle Despagnet-Ayoub教授和其他同事。该光谱仪可用于各种领域的研究，例如加速具有重要经济意义的化学反应，以及允许研究生物相关物种。一般来说，NMR光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。该仪器是该学院和附近其他机构的化学和生物化学本科生的教学、研究和研究培训的一个组成部分。授予NMR光谱仪的目的是加强各级的研究和教育。特别是对碳-碳键合成方法的探索和金属氧代涂层碳电极上碳-氢键电催化氧化的研究具有重要影响。该仪器还用于探索从能量存储到聚合物合成的各种项目。此外，它有利于芳烃脱芳构化反应的研究，为天然产物的合成。该光谱仪还用于研究多价噬菌体上显示的硫酸化配体的肝素样抗凝活性。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。