Analytical and Preparative Enantioselective Chromatography

分析和制备对映选择性色谱法

• 批准号: LE0883096
• 负责人: Prof James De Voss
• 金额: $ 40.01万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2009-02-17
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0883096
• 关键词: Analytical; Preparative; Enantioselective; Chromatography

Enantiomers are forms of the same molecule that are non-superimposable mirror images of one another, like a left hand and a right hand. Because they are so similar they are very difficult to separate. However, they have very different biological properties, such as when used as drugs. One enantiomer may be beneficial while the other has no effect or sometimes is even toxic. Therefore it is important to be able to tell how much of each enantiomer is present in a sample and to be able to separate them. This facility will allow us to do both of these things.

对映异构体是同一分子的形式，它们彼此是不可重叠的镜像，就像左手和右手。 因为它们非常相似，所以很难分开。 然而，它们具有非常不同的生物学特性，例如用作药物时。 一种对映异构体可能是有益的，而另一种对映异构体没有作用，有时甚至是有毒的。 因此，重要的是能够分辨样品中存在多少每种对映异构体并能够将它们分离。 这个设施将允许我们做这两件事。