CAREER: Establishing a Knowledge Base for Use and Discharge of Poly- and Perfluoroalkyl Substances

事业：建立多氟烷基物质和全氟烷基物质的使用和排放知识库

• 批准号: 2144550
• 负责人: Daqian Jiang
• 金额: $ 52.47万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2144550&HistoricalAwards=false
• 关键词: CAREER; Establishing; Knowledge; Base; Use

Per- and polyfluoroalkyl substances (PFAS) are fluorinated organic chemicals that have been used in numerous consumer products and industrial applications since the 1940s. PFAS are one of the most stable chemicals ever produced. During the last two decades, increasing detection of PFAS in environmental media (including air, water, soils, and biota) has raised significant concerns about their persistence, stability, and adverse impact in the environment including toxicity to living organisms and humans. A critical challenge in the management and mitigation of PFAS contamination in the United States (US) is the lack of curated data and systematic knowledge on the flows, emissions, and discharges of PFAS over their entire manufacturing, supply chain, and product life cycles. The overarching goal of this CAREER project is to develop and validate system analysis and modeling tools that could be used to 1) estimate the total use, accumulation, and discharge of PFAS in the US and 2) help identify the Nation’s geographic hotspots and economic drivers of PFAS contamination. To advance this goal, the Principal Investigator proposes to carry out an integrated data collection and modeling research program structured around two thrusts. Thrust 1 will collect and synthesize available measurements of PFAS uses and emissions (including spatial and temporal data) into a national material flow analysis to generate an integrated data set that can inform and improve PFAS risk assessment and management. Thrust 2 will operationalize multi-disciplinary techniques to guide the safer management of PFAS including the evaluation of the supply-chain and socio-economic drivers of PFAS utilization and consumption in the US. The successful completion of this project will benefit society through the development and validation of new system analysis and modeling tools to guide and support the development and implementation of more effective PFAS risk assessment, management, and mitigation strategies in the US. Additional benefits to society will be achieved through outreach and educational activities including the mentoring of a post-doctorate research fellow, a graduate student, and an undergraduate student at the University of Alabama Tuscaloosa.In the United States (US), various programs, policies, and regulations, ranging from product phaseout to new drinking water health advisories, are currently being developed to manage and mitigate the risks of PFAS contamination to human and ecosystem health. However, the effectiveness of these measures cannot be assessed accurately due to critical knowledge gaps including a lack of system-level knowledge and spatially integrated information about PFAS usages, emissions, and discharges throughout the entire product life cycles. This CAREER project will address these knowledge gaps. The specific objectives of the research are to develop and validate system analysis and modeling tools to: 1) Quantify system-wide use, accumulation, emissions, and discharge of PFAS based on past and future product usage scenarios; 2) Spatially delineate PFAS accumulation and emissions; 3) Characterize the supply-chain and socio-economic drivers of PFAS use; and 4) Estimate the global sensitivity of PFAS accumulation and emissions to methodological and data uncertainties. The successful completion of this project has the potential for transformative impact through 1) the generation of curated data sets on PFAS usages, emissions, and discharges in the US and 2) the development and validation of system analysis and modeling tools to guide and support PFAS risk management and mitigation programs in the US. To implement the educational and training goals of this CAREER project, the Principal Investigator (PI) proposes to develop and teach a new Industrial Ecology course for senior/graduate students at the University of Alabama (UA) Tuscaloosa. In addition, the PI plans to mentor undergraduate students at UA Tuscaloosa and organize immersive summer workshops on material sustainability research to facilitate exchange, networking, and collaboration between faculty and students from US, Asian, and European academic institutions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

全氟烷基物质和多氟烷基物质 (PFAS) 是氟化有机化学品，自 20 世纪 40 年代以来已用于众多消费品和工业应用。 PFAS 是迄今为止生产的最稳定的化学品之一。在过去的二十年中，环境介质（包括空气、水、土壤和生物群）中 PFAS 的检测量不断增加，引起了人们对其持久性、稳定性以及对环境的不利影响（包括对生物体和人类的毒性）的严重关注。在美国，管理和缓解 PFAS 污染的一个关键挑战是缺乏关于 PFAS 在整个制造、供应链和产品生命周期中的流动、排放和排放的整理数据和系统知识。该 CAREER 项目的总体目标是开发和验证系统分析和建模工具，可用于 1) 估计美国 PFAS 的总使用、累积和排放量，2) 帮助确定美国的地理热点和 PFAS 污染的经济驱动因素。为了推进这一目标，首席研究员建议围绕两个主旨开展一项综合数据收集和建模研究计划。主旨 1 将收集 PFAS 使用和排放的可用测量数据（包括空间和时间数据），并将其综合到国家物质流分析中，以生成综合数据集，为 PFAS 风险评估和管理提供信息并改进。 Thrust 2 将运用多学科技术来指导 PFAS 的更安全管理，包括评估美国 PFAS 使用和消费的供应链和社会经济驱动因素。该项目的成功完成将通过开发和验证新的系统分析和建模工具来指导和支持美国更有效的 PFAS 风险评估、管理和缓解策略的开发和实施，从而造福社会。通过外展和教育活动，包括指导阿拉巴马大学塔斯卡卢萨分校的一名博士后研究员、一名研究生和一名本科生，将给社会带来额外的好处。在美国，目前正在制定各种计划、政策和法规，从产品逐步淘汰到新的饮用水健康建议，以管理和减轻 PFAS 污染对人类和生态系统的风险 健康。然而，由于存在严重的知识差距，包括缺乏有关整个产品生命周期中 PFAS 使用、排放和排放的系统级知识和空间综合信息，因此无法准确评估这些措施的有效性。该职业项目将解决这些知识差距。该研究的具体目标是开发和验证系统分析和建模工具，以： 1) 根据过去和未来的产品使用场景，量化 PFAS 的全系统使用、积累、排放和排放； 2) 空间描绘 PFAS 积累和排放； 3) 描述 PFAS 使用的供应链和社会经济驱动因素； 4) 估计全球 PFAS 积累和排放对方法和数据不确定性的敏感性。该项目的成功完成可能会产生变革性影响，具体体现在：1) 生成有关美国 PFAS 使用、排放和排放的精选数据集；2) 开发和验证系统分析和建模工具，以指导和支持美国的 PFAS 风险管理和缓解计划。为了实现该职业项目的教育和培训目标，首席研究员 (PI) 建议为阿拉巴马大学 (UA) 塔斯卡卢萨分校的高年级/研究生开发和教授一门新的工业生态学课程。此外，PI 计划指导 UA 塔斯卡卢萨分校的本科生，并组织关于材料可持续性研究的沉浸式夏季研讨会，以促进来自美国、亚洲和欧洲学术机构的教师和学生之间的交流、网络和合作。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。