CAREER: Establishing a Knowledge Base for Use and Discharge of Poly- and Perfluoroalkyl Substances

事业：建立多氟烷基物质和全氟烷基物质的使用和排放知识库

• 批准号: 2144550
• 负责人: Daqian Jiang
• 金额: $ 52.47万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2144550&HistoricalAwards=false
• 关键词: CAREER; Establishing; Knowledge; Base; Use

Per- and polyfluoroalkyl substances (PFAS) are fluorinated organic chemicals that have been used in numerous consumer products and industrial applications since the 1940s. PFAS are one of the most stable chemicals ever produced. During the last two decades, increasing detection of PFAS in environmental media (including air, water, soils, and biota) has raised significant concerns about their persistence, stability, and adverse impact in the environment including toxicity to living organisms and humans. A critical challenge in the management and mitigation of PFAS contamination in the United States (US) is the lack of curated data and systematic knowledge on the flows, emissions, and discharges of PFAS over their entire manufacturing, supply chain, and product life cycles. The overarching goal of this CAREER project is to develop and validate system analysis and modeling tools that could be used to 1) estimate the total use, accumulation, and discharge of PFAS in the US and 2) help identify the Nation’s geographic hotspots and economic drivers of PFAS contamination. To advance this goal, the Principal Investigator proposes to carry out an integrated data collection and modeling research program structured around two thrusts. Thrust 1 will collect and synthesize available measurements of PFAS uses and emissions (including spatial and temporal data) into a national material flow analysis to generate an integrated data set that can inform and improve PFAS risk assessment and management. Thrust 2 will operationalize multi-disciplinary techniques to guide the safer management of PFAS including the evaluation of the supply-chain and socio-economic drivers of PFAS utilization and consumption in the US. The successful completion of this project will benefit society through the development and validation of new system analysis and modeling tools to guide and support the development and implementation of more effective PFAS risk assessment, management, and mitigation strategies in the US. Additional benefits to society will be achieved through outreach and educational activities including the mentoring of a post-doctorate research fellow, a graduate student, and an undergraduate student at the University of Alabama Tuscaloosa.In the United States (US), various programs, policies, and regulations, ranging from product phaseout to new drinking water health advisories, are currently being developed to manage and mitigate the risks of PFAS contamination to human and ecosystem health. However, the effectiveness of these measures cannot be assessed accurately due to critical knowledge gaps including a lack of system-level knowledge and spatially integrated information about PFAS usages, emissions, and discharges throughout the entire product life cycles. This CAREER project will address these knowledge gaps. The specific objectives of the research are to develop and validate system analysis and modeling tools to: 1) Quantify system-wide use, accumulation, emissions, and discharge of PFAS based on past and future product usage scenarios; 2) Spatially delineate PFAS accumulation and emissions; 3) Characterize the supply-chain and socio-economic drivers of PFAS use; and 4) Estimate the global sensitivity of PFAS accumulation and emissions to methodological and data uncertainties. The successful completion of this project has the potential for transformative impact through 1) the generation of curated data sets on PFAS usages, emissions, and discharges in the US and 2) the development and validation of system analysis and modeling tools to guide and support PFAS risk management and mitigation programs in the US. To implement the educational and training goals of this CAREER project, the Principal Investigator (PI) proposes to develop and teach a new Industrial Ecology course for senior/graduate students at the University of Alabama (UA) Tuscaloosa. In addition, the PI plans to mentor undergraduate students at UA Tuscaloosa and organize immersive summer workshops on material sustainability research to facilitate exchange, networking, and collaboration between faculty and students from US, Asian, and European academic institutions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

自1940年代以来，多氟烷基物质（PFA）是氟化有机化学物质，已在众多消费产品和工业应用中使用。 PFA是有史以来最稳定的化学物质之一。在过去的二十年中，在环境媒体（包括空气，水，土壤和生物群）中对PFA的发现增加了对环境对环境的持久性，稳定性和不利影响的重大关注，包括对生活组织和人类的毒性。美国（美国）的管理和缓解PFA污染的一项关键挑战是缺乏对PFA的流量，排放和排放在整个制造，供应链和产品寿命周期中的流量，排放和排放的系统知识。该职业项目的总体目标是开发和验证可用于使用的系统分析和建模工具1）估计美国PFA的总使用，积累和排放和2）2）帮助确定国家的地理热点和PFAS污染的经济驱动因素。为了促进这一目标，首席研究员的建议提出了进行综合数据收集和建模研究计划，该计划围绕两个推力。推力1将收集并合成可用的PFA用途和排放（包括空间和临时数据）的可用测量，以生成可以为PFAS风险评估和管理提供信息和改善PFAS风险评估和管理的集成数据集。推力2将操作多学科技术，以指导PFA的安全管理，包括评估美国PFA的供应链和社会经济驱动因素和美国的消费。该项目的成功完成将通过开发和验证新的系统分析和建模工具来使社会受益，以指导和支持美国更有效的PFA风险评估，管理和缓解策略。通过宣传和教育活动将获得对社会的更多好处 健康。但是，由于关键的知识差距，包括缺乏系统级知识以及有关PFA的使用，排放和放电的空间整合信息，因此无法准确评估这些措施的有效性。这个职业项目将解决这些知识差距。该研究的具体目标是开发和验证系统分析和建模工具：1）根据过去和将来的产品使用情况，量化系统范围内的使用，积累，排放和排放； 2）在空间上描绘了PFA的积累和排放； 3）表征PFA使用的供应链和社会经济驱动因素； 4）估计PFA的积累和排放对方法论和数据不确定性的全球敏感性。该项目的成功完成具有通过1）在美国的PFA使用，排放和放电的策划数据集以及2）制定和验证系统分析和建模工具的开发和验证以指导和支持PFAS风险管理和缓解计划的工具的潜力。为了实施该职业项目的教育和培训目标，首席研究员（PI）的建议是为阿拉巴马大学（UA）Tuscaloosa开发和教授新的工业生态学课程。此外，PI计划在UA Tuscaloosa的心理本科生计划，并组织了有关物质可持续性研究的沉浸式夏季研讨会，以促进我们，亚洲和欧洲学术机构的教职员工与学生之间的交流，网络和合作。该奖项通过评估了NSF的批准，这反映了NSF的法规范围，并在评估范围内对基础进行了评估，这是对基础的支持。