Conference: Broadening Participation and Supporting Early-Career Scientists at the International Polyploidy Conference, May 9-12, 2023 in Palm Coast (FL)

会议：扩大参与并支持早期职业科学家于 2023 年 5 月 9 日至 12 日在棕榈海岸（佛罗里达州）举行的国际多倍体会议

• 批准号: 2327644
• 负责人: Pamela Soltis
• 金额: $ 2.5万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2327644&HistoricalAwards=false
• 关键词: Conference; Broadening; Participation; Supporting; Early

Polyploidy (whole-genome duplication; WGD), the possession of three or more complete sets of chromosomes, characterizes the genomes of most eukaryotes. WGD is central to the study of genetics, evolution, ecology, as well as agriculture and medicine. Nearly all agricultural crops are polyploid, as are many human organs (e.g., the liver, heart, and placenta), and at least one third of all cancers arise from WGD. Despite the importance of WGD, our understanding of this critically important speciation mechanism and source of raw material for genomic and phenotypic evolution is both limited and disjointed. The International Polyploidy Conference entitled “Polyploidy Across the Tree of Life”, to be held May 9-12, 2023 (Palm Coast, FL) brings together researchers across diverse fields—cell biology, physiology, evolution, ecology, genomics, agriculture, and cancer—to discuss and identify commonalities that derive from shared polyploid cellular processes across organismal diversity, levels of biological organization, and fields of inquiry. NSF funds will be used to help support early-career researchers to attend the conference and participate in various networking and training opportunities. A central goal of the Polyploidy Across the Tree of Life Conference is to help uncover both the commonalities and distinct roles of WGD across lineages of the Tree of Life and at diverse levels of biological organization, i.e., gene regulation, cell function, organ formation, organismal performance, ecological responses, and landscape-level species distribution. This conference, with representation across currently siloed research fields of WGD, will promote dialogue and interactions that will hopefully lead to new, synthetic understanding of polyploidy and provide a foundation for translational innovations – from biodiversity and biocomplexity to medicine and agriculture. To date, no single conference has explicitly addressed establishment, evolution, stress, development, and disease or considered polyploidy across major clades of life. Supporting the participation and training of early career investigators in the exploration of these topics in diverse organisms at the conference will hopefully stimulate new directions in polyploidy research by a new generation of scientists. In addition, the use of NSF funds will help support efforts to maximize diversity across multiple axes: scientific discipline, perspective, country, geography, gender, race, ethnicity, institution, and career stage.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

多倍体（全基因组复制；WGD），拥有三组或更多完整的染色体，是大多数真核生物基因组的特征。 WGD 是遗传学、进化论、生态学以及农业和医学研究的核心。几乎所有农作物都是多倍体，许多人体器官（例如肝脏、心脏和胎盘）也是多倍体，所有癌症中至少三分之一是由全基因组测序引起的。尽管全基因组测序很重要，但我们对这一至关重要的物种形成机制以及基因组和表型进化的原材料来源的理解既有限又不连贯。题为“生命之树的多倍体”的国际多倍体会议将于 2023 年 5 月 9 日至 12 日（佛罗里达州棕榈海岸）举行，汇聚细胞生物学、生理学、进化、生态学、基因组学、农业和癌症等不同领域的研究人员，讨论和确定跨生物体多样性、生物组织水平和研究领域的共享多倍体细胞过程的共性。 NSF 资金将用于帮助支持早期职业研究人员参加会议并参与各种网络和培训机会。 生命之树多倍体会议的中心目标是帮助揭示生命之树谱系和生物组织不同层面（即基因调控、细胞功能、器官形成、有机体性能、生态反应和景观层面物种分布）WGD 的共性和独特作用。这次会议的代表涵盖了目前 WGD 孤立的研究领域，将促进对话和互动，有望带来对多倍体的新的综合理解，并为从生物多样性和生物复杂性到医学和农业的转化创新奠定基础。迄今为止，还没有任何一次会议明确讨论了建立、进化、压力、发育和疾病，或考虑了生命主要分支的多倍体。支持早期职业研究人员在会议上探索不同生物体中的这些主题的参与和培训将有望激发新一代科学家多倍体研究的新方向。此外，NSF 资金的使用将有助于支持在多个轴上最大限度地实现多样性的努力：科学学科、观点、国家、地理、性别、种族、族裔、机构和职业阶段。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。