Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS) Core Facility (S01)

液相色谱串联质谱 (LC-MS/MS) 核心设施 (S01)

• 批准号: 259942635
• 金额: --
• 依托单位: Klinik für Endokrinologie, Diabetologie, Stoffwechselkrankheiten und Klinische Chemie
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/259942635?language=en
• 关键词: Liquid; Chromatography; Tandem; Mass; Spectrometry

The service project, S01, connects the mass spectrometry platforms of Internal Medicine I and the Centre for Organismal Studies with the aim of providing consortium members the means to perform quantitative analysis of reactive metabolites, and their associated post-translational modifications, in relation to changes in core metabolism. The implementation of novel protocols and metabolomics techniques, such as 13C/15N tracing, will be a major focus for the future research program, thereby providing the prerequisites for translational applications.

该服务项目S 01连接了内科I和有机体研究中心的质谱平台，旨在为联盟成员提供对反应性代谢物及其相关翻译后修饰进行定量分析的方法，这些代谢物与核心代谢的变化有关。实施新的协议和代谢组学技术，如13 C/15 N示踪，将是未来研究计划的主要重点，从而为转化应用提供先决条件。