Dynamics of oculomotor adaptation and its interaction with perception

动眼适应的动力学及其与知觉的相互作用

• 批准号: 264811930
• 负责人: Professor Dr. Martin Rolfs
• 金额: --
• 依托单位: Institut für Psychologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/264811930?language=en
• 关键词: Dynamics; oculomotor; adaptation; its; interaction

Saccadic eye movements are the visual system´s dexterous camera work that allows exploration of the fine details of a visual scene. Maintaining their accuracy during arousal and fatigue, throughout developmental or pathological modifications, is thus of primary importance for our ability to see and act. This project aims to further our understanding of behavioral plasticity in the visuo-motor system of healthy adult participants by investigating the dynamics of saccadic adaptation across time-scales ranging from 1 to 100,000 saccades. We propose novel, sensitive paradigms and analyses to investigate the spatiotemporal evolution that characterizes saccadic adaptation following sequences of saccadic errors. Our project has three major goals. The first is to establish the temporal profile of saccadic adaptation. Adaptation has been reported to occur on very short time-scales, adjusting saccade amplitudes from trial to trial, but also on longer time-scales, up to several days. We aim to uncover the temporal resolution of adaptive amplitude changes by answering several questions: Does adaptation occur as a consequence of single saccades and what is the sensitivity of the system on such short time-scale? Do slow fluctuations in saccadic errors affect the state of adaptation and how flexibly does saccadic plasticity adjust to the statistics of such regularities? Our second goal is to understand the spatial profile of saccadic adaptation. Saccadic adaptation has been reported to be a local phenomenon, selective for particular saccade metrics, but can also evolve rapidly on a global scale, affecting saccades of all metrics. By investigating how vector-specificity evolves across time, we hope to provide a unified account of these two findings. Finally, we aim to investigate the interplay between saccadic adaptation and visual perception. Perceptual sensitivity to the saccade errors that cause adaptation may influence how adaptation unfolds, and how adaptation occurs concurrently with changes in the perception of space. We plan to apply the procedures used to determine the temporal resolution of adaptation to understand the dynamic interactions of motor and perceptual changes. By tackling these key questions in the field of saccadic adaptation with a set of innovative methods, we will map out the sensitivity of the visuo-motor system to incongruities between our movements and their visual goals.

扫视眼球运动是视觉系统灵巧的相机工作，允许探索视觉场景的细节。因此，在觉醒和疲劳期间，在整个发育或病理变化过程中，保持它们的准确性对我们的视觉和行动能力至关重要。该项目旨在通过调查从1到100，000次扫视的时间尺度上的扫视适应动态来进一步了解健康成年参与者视觉运动系统中的行为可塑性。我们提出了新的，敏感的范例和分析，调查时空演变的特点扫视适应以下序列的扫视错误。我们的项目有三个主要目标。首先是建立扫视适应的时间轮廓。据报道，适应发生在非常短的时间尺度上，从一次试验到另一次试验调整扫视幅度，但也发生在更长的时间尺度上，长达几天。我们的目标是通过回答几个问题来揭示自适应幅度变化的时间分辨率：适应是否会发生单次扫视的结果，以及系统在如此短的时间尺度上的灵敏度是什么？扫视误差的缓慢波动是否会影响适应状态？扫视可塑性如何灵活地适应这种波动的统计数据？我们的第二个目标是了解扫视适应的空间轮廓。据报道，扫视适应是一种局部现象，对特定的扫视指标有选择性，但也可以在全球范围内迅速演变，影响所有指标的扫视。通过研究载体特异性如何随时间演变，我们希望为这两个发现提供一个统一的解释。最后，我们的目标是调查扫视适应和视觉感知之间的相互作用。对引起适应的扫视错误的感知敏感性可能会影响适应如何展开，以及适应如何与空间感知的变化同时发生。我们计划应用程序来确定适应的时间分辨率，以了解运动和感知变化的动态相互作用。通过用一套创新的方法解决扫视适应领域的这些关键问题，我们将绘制出视觉运动系统对我们的运动和他们的视觉目标之间的不一致的敏感度。

项目成果

Probing transsaccadic correspondence with reverse correlation.

通过逆相关探测跨眼跳对应关系

• DOI: 10.1167/18.3.10
• 发表时间: 2018
• 期刊: Journal of vision
• 影响因子: 1.8
• 作者: Joosten;Collins
• 通讯作者: Collins

Failure to use corollary discharge to remap visual target locations is associated with psychotic symptom severity in schizophrenia.

未能使用推论放电重新映射视觉目标位置与精神分裂症的精神病症状严重程度相关

• DOI: 10.1152/jn.00155.2015
• 发表时间: 2015
• 期刊: Journal of neurophysiology
• 影响因子: 2.5
• 作者: Rösler;van der Stigchel;Neggers;Thakkar
• 通讯作者: Thakkar

Structural Thalamofrontal Hypoconnectivity Is Related to Oculomotor Corollary Discharge Dysfunction in Schizophrenia

• DOI: 10.1523/jneurosci.1473-18.2019
• 发表时间: 2019-01
• 期刊: The Journal of Neuroscience
• 作者: Beier Yao;S. Neggers;M. Rolfs;L. Rösler;Ilse A Thompson;H. Hopman;Livon Ghermezi;R. Kahn;Katharine N. Thakkar