Total Synthesis and Biological Evaluation of Australian Sponge Metabolites

澳大利亚海绵代谢物的全合成及生物学评价

• 批准号: DP0771749
• 负责人: Prof Martin Banwell
• 金额: $ 37.12万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0771749
• 关键词: Total; Synthesis; Biological; Evaluation; Australian

The development of functional syntheses of Australian natural products and certain analogues of ecological and therapeutic significance will emerge. Such activities will lead to the identification and evaluation of molecular entities of value in managing marine environments, reduce the need for removal of organisms from marine environments both within and outside of Australia as well as helping maintain and enhance chemical synthesis capacity within the country. The proposed studies could lead to the identification of related natural products produced by organisms on the Great Barrier Reef and that may display even more potent activities and/or complementary ecological roles.

澳大利亚天然产物和某些具有生态和治疗意义的类似物的功能性合成的发展将出现。这些活动将导致查明和评价在管理海洋环境方面有价值的分子实体，减少从澳大利亚境内外海洋环境中清除生物的需要，并帮助维持和加强国内的化学合成能力。拟议的研究可能会导致识别大堡礁生物产生的相关天然产物，并可能显示出更有效的活动和/或互补的生态作用。