Synthetic, Molecular and Biological Studies on Novel Marine Metabolites Isolated from Great Barrier Reef Sponges
Synthetic, Molecular and Biological Studies on Novel Marine Metabolites Isolated from Great Barrier Reef Sponges
批准号:
DP0450057
负责人:
Prof Martin Banwell
金额:
$43.87万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2007-12-31
中文摘要
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英文摘要
Whilst structurally remarkable marine natural products, generated via unprecedented biosynthetic pathways, continue to be isolated from organisms found on the Barrier Reef these substances remain largely unexploited in terms of both their potent biological and ecological properties. Efficient syntheses of two classes of marine metabolites will be undertaken to allow biological, biosynthetic and ecological evaluation of advanced intermediates and final products. Such evaluations will provide new insights into the therapeutic and ecological potential as well as the origins of these natural products. New agents for the management of marine ecosystems and the treatment of oncological and other diseases should emerge.
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