Rapid evolution of gene regulation

环境条件的改变可以导致基因表达的快速适应性变化。本计画旨在了解黑腹果蝇自然族群的顺式调控演化。使用高通量RNA测序（RNA-seq）和报告基因实验，我们将确定影响基因表达的遗传变异。此外，我们将确定它们对基因表达的影响程度，并研究它们的种群动态。

Alterations in environmental conditions can lead to rapid, adaptive changes in gene expression. This project aims to understand cis-regulatory evolution in natural populations of the fruit fly Drosophila melanogaster. Using high-throughput RNA sequencing (RNA-seq) and reporter gene experiments, we will identify genetic variants that influence gene expression. Furthermore, we will determine the magnitude of their effect on gene expression and investigate their population dynamics.