Bringing diamond quantum sensors into application in biology and chemistry

将金刚石量子传感器应用于生物和化学领域

• 批准号: 277454479
• 负责人: Professor Dr. Dominik Benjamin Bucher
• 金额: --
• 依托单位: Lehrstuhl für Physikalische Chemie
• 依托单位国家: 德国
• 项目类别: Research Fellowships
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2016-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/277454479?language=en
• 关键词: Bringing; diamond; quantum; sensors; into

Major advances and insights in natural sciences are often catalyzed by the development of innovative experimental tools. In recent years a new experimental technique based on nitrogen-vacancy (NV) color centers in diamond has been established which is a combination of sensitive fluorescence microscopy and NMR/MRI techniques. The fluorescence of these defects in the diamond lattice is sensitive to external influences like magnetic and electric fields. This property enables the ultrasensitive measurement of magnetic fields on the nanoscale, for example the detection of single electron or nuclear spins as well as magnetic fields in living cells. Whereas many experiments have demonstrated the extraordinary properties of this quantum sensor, biological and chemical problems have not been addressed directly so far. That is why the main aim of this proposal is to bring the diamond quantum sensors into application in biology and chemistry. The outstanding properties of this nanosensor shall be used to detect magnetic plaques in the brains of Alzheimers and Parkinsons patients. In addition, the NV-centers shall be used to determine the activity of neurons and to identify single DNA molecules. These experiments will give new insights into current biological and biochemical problems.

自然科学的重大进步和见解往往是由创新实验工具的发展催化的。近年来，将灵敏的荧光显微镜和核磁共振/磁共振技术相结合，建立了一种新的基于金刚石中氮空位色心的实验技术。金刚石晶格中这些缺陷的荧光对磁场和电场等外部影响敏感。这种特性使得能够在纳米尺度上对磁场进行超灵敏的测量，例如检测单电子或核自旋以及活细胞中的磁场。虽然许多实验已经证明了这种量子传感器的非凡特性，但迄今为止还没有直接解决生物和化学问题。这就是为什么这个提议的主要目的是将金刚石量子传感器应用于生物和化学。这种纳米传感器的突出特性将用于检测阿尔茨海默病和帕金森病患者大脑中的磁斑。此外，NV中心应用于确定神经元的活性和识别单个DNA分子。这些实验将为当前的生物学和生物化学问题提供新的见解。