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Rational Optimisation of the Uptake of Metal-Based Anti-Cancer Agents by Tumours

Rational Optimisation of the Uptake of Metal-Based Anti-Cancer Agents by Tumours
肿瘤对金属抗癌药物摄取的合理优化
批准号:
DP0773953
负责人:
Em/Prof Trevor Hambley
金额:
$20.82万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2007
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2007-01-23 至 2010-06-30

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中文摘要
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英文摘要
In this project will develop an understanding of how anticancer drugs are taken up, distributed and modified in tumours. The information gathered will be of value to all those developing new anticancer drugs and we will then use it to develop new drugs that more selectively target tumours and therefore have reduced side effects. Successful development of less toxic anticancer agents would lead to less debilitating treatment, more effective treatment, and an increase in the number of patients effectively treated. Effective anticancer drugs can also be very large income earners for Australia.
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Fluorescent sensing of the intracellular redox environment
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
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Novel platinum(IV) complexes that are targeted to and trapped by tumours and tumour cells
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Development of prodrug strategies for achieving increased penetration and selective activation in solid tumours
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  • 项目类别:
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    2011
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Radiolabelled MMP binding agents for the identification, quantification, and targeting of MMPs in central nervous system (CNS) disorders and tumours
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  • 负责人:
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