Rational Optimisation of the Uptake of Metal-Based Anti-Cancer Agents by Tumours
肿瘤对金属抗癌药物摄取的合理优化
基本信息
- 批准号:DP0773953
- 负责人:
- 金额:$ 20.82万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Discovery Projects
- 财政年份:2007
- 资助国家:澳大利亚
- 起止时间:2007-01-23 至 2010-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
In this project will develop an understanding of how anticancer drugs are taken up, distributed and modified in tumours. The information gathered will be of value to all those developing new anticancer drugs and we will then use it to develop new drugs that more selectively target tumours and therefore have reduced side effects. Successful development of less toxic anticancer agents would lead to less debilitating treatment, more effective treatment, and an increase in the number of patients effectively treated. Effective anticancer drugs can also be very large income earners for Australia.
在这个项目中,将了解抗癌药物如何在肿瘤中被吸收,分布和修饰。收集的信息将对所有开发新抗癌药物的人有价值,然后我们将利用它来开发更有选择性地靶向肿瘤的新药,从而减少副作用。成功开发毒性较小的抗癌药物将导致更少的衰弱治疗,更有效的治疗,并增加有效治疗的患者数量。有效的抗癌药物也可以为澳大利亚带来很大的收入。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Em/Prof Trevor Hambley其他文献
Em/Prof Trevor Hambley的其他文献
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{{ truncateString('Em/Prof Trevor Hambley', 18)}}的其他基金
Fluorescent sensing of the intracellular redox environment
细胞内氧化还原环境的荧光传感
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Novel platinum(IV) complexes that are targeted to and trapped by tumours and tumour cells
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Development of prodrug strategies for achieving increased penetration and selective activation in solid tumours
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DP110100461 - 财政年份:2011
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Radiolabelled MMP binding agents for the identification, quantification, and targeting of MMPs in central nervous system (CNS) disorders and tumours
放射性标记的 MMP 结合剂,用于中枢神经系统 (CNS) 疾病和肿瘤中 MMP 的识别、定量和靶向
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DP1094232 - 财政年份:2010
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$ 20.82万 - 项目类别:
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Functionalised MMP Inhibitors as Radiodiagnostic, Radiotherapeutic, and Radiation-Sensitising Agents for Metastatic Cancer
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Probing and Developing Hypoxia-Selective Anti-Cancer Agents
探索和开发缺氧选择性抗癌药物
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DP0450122 - 财政年份:2004
- 资助金额:
$ 20.82万 - 项目类别:
Discovery Projects
Ultra-Sensitive CCD Diffractometer with High Intensity X-ray Photon Generator
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LE0346733 - 财政年份:2003
- 资助金额:
$ 20.82万 - 项目类别:
Linkage Infrastructure, Equipment and Facilities
Development and Biological Chemistry of Novel Platinum Anti-Cancer Agents
新型铂类抗癌药物的开发及生物化学
- 批准号:
DP0344085 - 财政年份:2003
- 资助金额:
$ 20.82万 - 项目类别:
Discovery Projects
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