Rational Optimisation of the Uptake of Metal-Based Anti-Cancer Agents by Tumours

在这个项目中，我们将进一步了解抗癌药物是如何在肿瘤中被吸收、分布和修饰的。收集到的信息将对所有开发新的抗癌药物的人有价值，然后我们将利用它来开发新的药物，更有选择性地针对肿瘤，从而减少副作用。成功开发出毒性较低的抗癌药物，将减少使人衰弱的治疗，提高治疗效果，并增加有效治疗的患者数量。有效的抗癌药物也能给澳大利亚带来巨大的收入。

In this project will develop an understanding of how anticancer drugs are taken up, distributed and modified in tumours. The information gathered will be of value to all those developing new anticancer drugs and we will then use it to develop new drugs that more selectively target tumours and therefore have reduced side effects. Successful development of less toxic anticancer agents would lead to less debilitating treatment, more effective treatment, and an increase in the number of patients effectively treated. Effective anticancer drugs can also be very large income earners for Australia.