Goal pursuit despite emotional distraction: Neural-network mechanisms of emotional interference inhibition and their role for resilience (C04)

情绪干扰抑制(EII)，即在情绪分散的情况下抑制显著的情绪刺激以追求目标导向的行为，被认为是一种普遍的弹性机制。在第一个资助期，我们已经确定了一个大脑网络，具有各种类型的EII共同的特定光谱特征，并与弹性的代理测量相关。利用信息论、药理学和神经调节的方法，我们现在的目标是获得对该网络的功能及其作为弹性机制的作用的机械性和因果的理解。

Emotional interference inhibition (EII), i.e., inhibition of salient emotional stimuli to pursue goal-directed behavior despite emotional distraction, is considered a general resilience mechanism. In the first funding period, we have identified a brain network with specific spectral signatures common to various types of EII and correlating with proxy measures of resilience. Using information theoretic, pharmacological and neuromodulatory approaches, we now aim to gain mechanistic and causal understanding of the function of this network and its role as a resilience mechanism.