Construction of drug discovery library using PDX-3D method and discovery of novel therapeutic agents for pancreatic cancer
Construction of drug discovery library using PDX-3D method and discovery of novel therapeutic agents for pancreatic cancer
批准号:
20H03754
负责人:
MIZUMOTO Kazuhiro
金额:
$11.32万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2020
资助国家:
日本
项目状态:
已结题
起止时间:
2020-04-01 至 2023-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
期刊论文(6)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
分化型膵癌は癌関連線維芽細胞由来の微小環境因子に依存して分化度を保持している
分化型胰腺癌根据来自癌症相关成纤维细胞的微环境因素来维持其分化程度。
DOI:
--
发表时间:
2021
期刊:
影响因子:
--
作者:
[新川智彦, 大内田研宙, 持田郁己, 小山虹輝, 林昌孝, 松本奏吉, 岩本千佳, 進藤幸治, 池永直樹, 仲田興平, 中村雅史]
通讯作者:
中村雅史
Efficient Targeted Therapy for Pancreatic Cancer Using Nanosystem and Focusing on the Suppression of Pancreatic Stellate Cell Activation
以抑制胰腺星状细胞活化为重点的纳米系统胰腺癌高效靶向治疗
DOI:
--
发表时间:
2020
期刊:
影响因子:
--
作者:
[Matsumoto S, Nakata K, Ikenaga N, Date S, Guan W, Sagara A, Ohuchida K, Ohtsuka T, Nakamura M]
通讯作者:
Nakamura M
膵癌における癌関連線維芽細胞由来の微小環境因子が腫瘍分化度に与える影響についての検討
癌症相关成纤维细胞来源的微环境因素对胰腺癌肿瘤分化程度的影响研究
DOI:
--
发表时间:
2021
期刊:
影响因子:
--
作者:
[新川智彦, 大内田研宙, 持田郁己, 奥田翔, 大坪慶志輝, 岩本千佳, 進藤幸治, 池永直樹, 仲田興平, 中村雅史]
通讯作者:
中村雅史
Investigation of the mechanism of PSC activation and development of high-throughput drug screening detecting compounds targeting PSC
PSC激活机制研究及针对PSC的高通量药物筛选检测化合物的开发
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
[Kohei Nakata, Toshiya Abe, Noboru Ideno, Naoki Ikenaga, Yusuke Mizuuchi, Kenoki Ohuchida, Masafumi Nakamura]
通讯作者:
Masafumi Nakamura
Induction of tumor-suppressing pancreatic stellate cell subpopulation by pancreatic cancer microenvironment reprogramming
-
批准号:15H04933
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.65万
-
财政年份:2015
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Biological and clinical significance of niche during carcinogenesis in pancreatic cancer
-
批准号:25670585
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2013
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Identification of the key stromal cell responsible for desmoplasia of pancreatic cancer, elucidation of the origin of it, and regulation of its function
-
批准号:24390319
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2012
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
A novel approach for early diagnosis and personalized therapy to pancreatic cancer by metabolic profiling
-
批准号:23659654
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2011
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Gene expressions in microdissected target cells as the diagnostic markers of pancreatic cancer and the prediction of treatment outcome using nano-technology
-
批准号:18390368
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.3万
-
财政年份:2006
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Development of genetic diagnosis system for pancreatic cancer using modified telomeric repeat amplification protocols and electrochemical array chip
-
批准号:15390399
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.34万
-
财政年份:2003
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
The role of Nitric oxide synthase andCytochrome P450 enzyme on the inhibitory effect of sevoflumae on vascular relaxation
-
批准号:14571463
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2002
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Anti-cancer chemoagents-triggered centrosome aberrance and its relationship with mitotic cell death in pancreatic cancer cells.
-
批准号:13671244
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2001
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
Molecular diagnosis of pancreatic cancer by telomerase
-
批准号:11671249
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
-
财政年份:1999
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
EFFECTS OF VOLATILE ANESTHETICS ON ENDOTHELIAL NITRIC OXIDE SYNTHESIS AND VASODILATION MEDIATED THOROUGH THE CaィイD12+ィエD1 INFLUX PROMOTED BY THE DEPLETION OF CaィイD12+ィエD1 IN ENDOPLASMIC RETICULUM
-
批准号:10671440
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1998
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
MECHANISTIC ANALYSIS AND ENHANCEMENT OF CELL DEATH OF HUMAN PANCREATIC CANCER CELL LINE EXPOSED BY HIGH DOSE X-RAY IRRADIATION - FOR THE IMPROVEMENT OF ADJUVANT CHEMOTHERPY OF PANCREATIC CANCER
-
批准号:08671457
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.45万
-
财政年份:1996
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
NECROSIS AND APORTOSIS OF HUMAN PANCREATIC CANCER CELL LINES-FOR THE IMPROVEMENT OF ADJUVANT CHEMOTHERAPY FOR PANCREATIC CANCER
-
批准号:06671289
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1994
-
负责人:MIZUMOTO Kazuhiro
-
依托单位:
海外基金