Novel treatment of refractory prostate cancer by targeting androgen receptor signaling and epithelial mesenchymal transition associated factors

通过靶向雄激素受体信号传导和上皮间质转化相关因子治疗难治性前列腺癌

• 批准号: 18K16709
• 负责人: YANAI YOSHINORI
• 金额: $ 2.66万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K16709/
• 关键词: 局所進行性前立腺癌; アンドロゲン受容体; 抗がん剤耐性; 上皮間葉転換; 精嚢浸潤; がん微小免疫環境; 前立腺癌; 被膜外浸潤; CD8; ZEB1; 去勢抵抗性前立腺癌; EMT誘導転写因子; 相互依存的制御機構; 上皮間葉細胞転換; クロストーク解明; 新規治療戦略

项目成果

Do all patients who have prostate cancer with seminal vesicle invasion have poor prognosis?

是否所有前列腺癌侵犯精囊的患者预后都很差？

• 发表时间: 2020
• 作者: Keitaro Iida;Taku Naiki;Aya Naiki;Toshiki Etani;Ryosuke Ando;Noriyasu Kawai;Satoru Takahashi;Takahiro Yasui;Yoshinori Yanai
• 通讯作者: Yoshinori Yanai

Locally advanced prostate cancer effected by the tumor immunoenvironment

受肿瘤免疫环境影响的局部晚期前列腺癌

• 发表时间: 2020
• 作者: Anan Go;Kaiho Yasuhiro;Iwamura Hiromichi;Ito Jun;Kohada Yuki;Mikami Jotaro;Sato Makoto;Yoshinori Yanai
• 通讯作者: Yoshinori Yanai

Not all patients who have prostate cancer with seminal vesicle invasion have poor prognosis

并非所有患有精囊侵犯的前列腺癌患者预后不良

• 发表时间: 2020
• 作者: Anan Go;Yoneyama Tohru;Noro Daisuke;Tobisawa Yuki;Hatakeyama Shingo;Sutoh Yoneyama Mihoko;Yamamoto Hayato;Imai Atsushi;Iwamura Hiromichi;Kohada Yuki;Mikami Jotaro;Ito Jun;Kaiho Yasuhiro;Yoneyama Takahiro;Hashimoto Yasuhiro;Sato Makoto;Ohyama Chikara;Yoshinori Yanai
• 通讯作者: Yoshinori Yanai