Learning From Nature: Energy Harvesting and Intersymbol Interference Mitigation via Reuptake of Information Molecules in Diffusive Molecular Communication Systems

向自然学习:通过扩散分子通信系统中信息分子的重新摄取来收集能量和减轻符号间干扰

基本信息

项目摘要

A major challenge in the design of synthetic diffusive molecular communication (DMC) systems is the intersymbol interference caused by the dispersive nature of molecule diffusion. Solutions to cope with this problem have been developed by nature for natural DMC systems. One interesting solution is found in certain chemical synapses where the information molecules are removed from the synaptic space by transporting them back into the presynaptic cell which facilitates their recycling for future reuse and can be interpreted as a form of energy harvesting. In dopaminergic synapses, this process is controlled by the dopamine transporter (DAT) protein and constitutes the major regulator of the dopamine (DA) neurotransmitter molecules in the synapse. The importance of this regulatory mechanism is evident from the numerous diseases associated with dysregulations of the transport mechanism. The main objective of the present project is to investigate the macroscopic effects of molecule reuptake on intersymbol interference mitigation and energy harvesting in natural and synthetic DMC systems. Although the developed concepts and analyses will be made as general as possible, special attention will be given to the DA/DAT system because of its physiological importance and the abundance of available experimental studies, which can be used for verification of the developed models and results. The outcomes of this project will improve our understanding of the impact of molecule reuptake in natural DMC systems and provide new design options for synthetic DMC systems.
在设计合成扩散分子通信(DMC)系统时面临的主要挑战是由分子扩散的色散特性引起的符号间干扰。自然界已经为自然DMC系统开发了解决这个问题的方法。在某些化学突触中发现了一个有趣的解决方案,其中信息分子通过将它们运送回突触前细胞而从突触空间中移除,这有助于它们的回收,以供将来再利用,并且可以解释为能量收集的一种形式。在多巴胺能突触中,这一过程由多巴胺转运蛋白(DAT)控制,并构成突触中多巴胺(DA)神经递质分子的主要调节剂。这种调节机制的重要性从与运输机制失调相关的许多疾病中可见一斑。本项目的主要目的是研究分子再吸收对天然和合成DMC系统中符号间干扰缓解和能量收集的宏观影响。虽然所提出的概念和分析将尽可能一般化,但将特别注意数据分析/数据分析系统,因为它在生理学上的重要性和现有的大量实验研究可用于验证所提出的模型和结果。该项目的结果将提高我们对天然DMC系统中分子再摄取影响的理解,并为合成DMC系统提供新的设计选择。

项目成果

期刊论文数量(7)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A Survey of Biological Building Blocks for Synthetic Molecular Communication Systems
  • DOI:
    10.1109/comst.2020.3008819
  • 发表时间:
    2020-01-01
  • 期刊:
  • 影响因子:
    35.6
  • 作者:
    Soeldner,Christian A.;Socher,Eileen;Sticht,Heinrich
  • 通讯作者:
    Sticht,Heinrich
Molecule Harvesting Transmitter Model for Molecular Communication Systems
分子通信系统的分子收集发射器模型
Channel Modeling for Synaptic Molecular Communication With Re-uptake and Reversible Receptor Binding
A Chemical Master Equation Model for Synaptic Molecular Communication
突触分子通讯的化学主方程模型
Synaptic Channel Modeling for DMC: Neurotransmitter Uptake and Spillover in the Tripartite Synapse
  • DOI:
    10.1109/tcomm.2020.3040318
  • 发表时间:
    2020-05
  • 期刊:
  • 影响因子:
    8.3
  • 作者:
    Sebastian Lotter;Arman Ahmadzadeh;R. Schober
  • 通讯作者:
    Sebastian Lotter;Arman Ahmadzadeh;R. Schober
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Professor Dr.-Ing. Robert Schober其他文献

Professor Dr.-Ing. Robert Schober的其他文献

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{{ truncateString('Professor Dr.-Ing. Robert Schober', 18)}}的其他基金

Signal Design and Optimization for Wireless Communication Systems Employing Nonlinear RF Energy Harvesting
采用非线性射频能量收集的无线通信系统的信号设计和优化
  • 批准号:
    414988357
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Massive MIMO Systems for Communication and Localization
用于通信和定位的大规模 MIMO 系统
  • 批准号:
    259038323
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Modeling, Optimization, and Hardware Design of Intelligent Reflecting Surface Assisted Wireless Communication Systems
智能反射面辅助无线通信系统的建模、优化和硬件设计
  • 批准号:
    454492702
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
    Research Grants

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CAREER: Understanding the Nature of Dark Energy with the Young Supernova Experiment and the Legacy Survey of Space and Time
职业:通过年轻超新星实验和时空遗产调查了解暗能量的本质
  • 批准号:
    2239364
  • 财政年份:
    2023
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    Standard Grant
Nature-inspired design and fabrication of nanostructured functional carbon for nextgen energy storage devices
用于下一代储能设备的纳米结构功能碳的受自然启发的设计和制造
  • 批准号:
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    2022
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Understanding the nature and origin of the highest energy cosmic rays
了解最高能量宇宙射线的性质和起源
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The nature and roles of cellular metabolism and energy in the regulation of neuronal chain migration
细胞代谢和能量在神经元链迁移调节中的性质和作用
  • 批准号:
    20K06865
  • 财政年份:
    2020
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    --
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    Grant-in-Aid for Scientific Research (C)
INFEWS: U.S.-China: Increasing the Resilience of Human-Nature Interactions in the Yellow River Basin through Coordinated Food-Energy-Water Nexus Management
INFEWS:中美:通过协调的粮食-能源-水关系管理提高黄河流域人与自然相互作用的弹性
  • 批准号:
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Nature-inspired Engineering of High-Performance Nanoporous Carbon Materials for Sustainable Energy and Environmental Applications
用于可持续能源和环境应用的高性能纳米多孔碳材料的受自然启发的工程
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    RGPIN-2014-04415
  • 财政年份:
    2018
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    --
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    Discovery Grants Program - Individual
Nature-inspired Engineering of High-Performance Nanoporous Carbon Materials for Sustainable Energy and Environmental Applications
用于可持续能源和环境应用的高性能纳米多孔碳材料的受自然启发的工程
  • 批准号:
    RGPIN-2014-04415
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A study on the impact of "community indicator" on behavioral change to enhance the social nature of energy-saving behavior
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Nature-inspired Engineering of High-Performance Nanoporous Carbon Materials for Sustainable Energy and Environmental Applications
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