The experimental production of the protein transport system to the cytoplasm.

肉毒杆菌祖毒素由一种神经毒素（NTX）和多种无毒成分组成，包括几种血凝素（HA）蛋白。口服的NTX在HA成分的帮助下通过上皮进入血液循环系统，特异性结合周围神经细胞，侵入细胞质，引起食源性肉毒杆菌中毒。在这项研究中，我们挑战了利用肉毒杆菌战术感染机制的新型药物递送系统（DDS）的发展，并获得了一些为新型DDS提供平台的结果。

Botulinum progenitor toxin consists of one neurotoxin (NTX) and multiple non-toxic components including several haemagglutinin (HA) proteins. Orally ingested NTX passes through the epithelial layer into the blood circulation system with the aide of HA components, and specifically binds to the peripheral nerve cells, and invades into cytoplasm, then causes food-borne botulism. In this study, we challenged the development of novel drug delivery system (DDS) utilizing the botulinum tactical infection mechanism, and a several results which provide a platform for novel DDS were obtained.