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The mechanisms of placebo effect on orofacial pain

The mechanisms of placebo effect on orofacial pain
安慰剂对口面部疼痛的作用机制
批准号:
24659831
负责人:
KOBAYASHI Masayuki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31

项目摘要

项目成果

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中文摘要
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英文摘要
The present study aimed to explore the activated brain regions responding to placebo effect in a model with orofacial pain. The experiments were divided into two steps: (1) establishment of the model for orofacial chronic pain that is suitable for estimation of placebo effect, and (2) PET imaging to estimate the activated brain regions in awake model rats. We found that the model with inferior alveolar nerve injury is suitable for this study. Furthermore, our PET imaging revealed that orofacial pain principally activated the primary somatosensory cortex.
期刊论文(14)
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会议论文
DOI: 10.1016/j.neuroscience.2013.01.012
发表时间: 2013-04-16
期刊: NEUROSCIENCE
影响因子: 3.3
作者: [Ebihara, K., Yamamoto, K., Kobayashi, M.]
通讯作者: Kobayashi, M.
DOI: 10.1111/eos.12021
发表时间: 2013-04
期刊: European journal of oral sciences
影响因子: 1.9
作者: [Kohei Teramoto;Y. Tsuboi;M. Shinoda;S. Hitomi;K. Abe;K. Kaji;Takaaki Tamagawa;Azumi Suzuki;N. Noma;Masayuki Kobayashi;O. Komiyama;K. Urata;K. Iwata]
通讯作者: Kohei Teramoto;Y. Tsuboi;M. Shinoda;S. Hitomi;K. Abe;K. Kaji;Takaaki Tamagawa;Azumi Suzuki;N. Noma;Masayuki Kobayashi;O. Komiyama;K. Urata;K. Iwata
Phenotypic characterisation of orofacial movement topography in mutants with disruption of amino acid mechanisms : glutamate N2A/B/D [GluRε1/2/4] subtypes and the GABA synthesising enzyme GAD65
氨基酸机制破坏的突变体口面部运动地形的表型特征:谷氨酸 N2A/B/D [GluRε1/2/4] 亚型和 GABA 合成酶 GAD65
DOI: --
发表时间: 2013
期刊: Neuroscience
影响因子: 3.3
作者: [Tomiyama K, Kato R, Hara Y, Kobayashi M, Mishina M, Yanagawa Y, Kinsella A, Koshikawa N, Waddington JL]
通讯作者: Waddington JL
DOI: 10.1097/aln.0000000000000183
发表时间: 2014-07-01
期刊: ANESTHESIOLOGY
影响因子: 8.8
作者: [Koyanagi, Yuko, Oi, Yoshiyuki, Kobayashi, Masayuki]
通讯作者: Kobayashi, Masayuki
13
    Mechanisms of insulocortical neural dynamics in the alert animals revealed by calcium imaging techniques
    • 批准号:
      21K19616
    • 项目类别:
      Grant-in-Aid for Challenging Research (Exploratory)
    • 资助金额:
      $4.08万
    • 财政年份:
      2021
    • 负责人:
      KOBAYASHI Masayuki
    • 依托单位:
    Mechanisms of insulocortical inhibitory synaptic transmission plasticity that regulates neuropathic pain
    • 批准号:
      19H03821
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.07万
    • 财政年份:
      2019
    • 负责人:
      KOBAYASHI Masayuki
    • 依托单位:
    Relationship between receptor expression revaled by rhodamine-labeled peptides and calcium responses in cortical neurons
    • 批准号:
      16K15783
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.16万
    • 财政年份:
      2016
    • 负责人:
      KOBAYASHI Masayuki
    • 依托单位:
    Trigeminal nerve transection-induced neuroplastic changes in the somatosensory and insular cortices in a rat ectopic pain model
    • 批准号:
      16H05507
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.07万
    • 财政年份:
      2016
    • 负责人:
      KOBAYASHI Masayuki
    • 依托单位:
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      省市级项目
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      --
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      2026
    • 负责人:
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    • 批准号:
      2026JJ70009
    • 项目类别:
      省市级项目
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    • 批准年份:
      2026
    • 负责人:
      张峰
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    α7nAChR重塑巨噬细胞铁死亡调控脊髓小胶质细胞在神经病理性疼痛中的作用及机制研究
    • 批准号:
      JCZRLH202601116
    • 项目类别:
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