Novel humoral factors regulating epigenomic status
Novel humoral factors regulating epigenomic status
批准号:
25670384
负责人:
YAMASHITA Jun
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2014-03-31
中文摘要
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英文摘要
This study aimed at identification of novel humoral factors that regulate epigenomic status. Following items were investigated; 1) Involvement of adrenomedullin in differentiation and adult physiology. 2) Investigation of novel factors regulating epigenome through PKA signaling. 3) Significance and functions of the identified factors. We succeeded in showing the involvement of AM in the regulation of differentiation timing from embryonic stem cells. We further identified one novel factor that also regulates differentiation timing and epigenomic status. Currently, we are analyzing functions of the factor in the adult mice.
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多能性幹細胞を用いた新しい心不全治療実現に向けた多面的アプローチ
使用多能干细胞实现新的心力衰竭治疗的多方面方法
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK, 山下潤, 山下潤, 山下潤, 山下潤, 山下潤]
通讯作者:
山下潤
多能性幹細胞を用いた心血管分化再生に関する多面的研究
利用多能干细胞进行心血管分化和再生的多方面研究
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK, 山下潤, 山下潤]
通讯作者:
山下潤
DOI:
10.1161/circgenetics.113.000330
发表时间:
2013-12
期刊:
Circulation. Cardiovascular genetics
影响因子:
--
作者:
[Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK]
通讯作者:
Yamashita JK
ES細胞/iPS細胞を用いた多面的心臓再生治療戦略の開発
使用ES细胞/iPS细胞开发多方面的心脏再生治疗策略
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK, 山下潤, 山下潤, 山下潤, 山下潤, 山下潤, Yamashita JK, 山下潤, 山下潤]
通讯作者:
山下潤
多能性幹細胞を用いて多面的に心臓再生に挑戦する
使用多能干细胞进行心脏再生的多方面挑战
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK, 山下潤, 山下潤, 山下潤, 山下潤, 山下潤, Yamashita JK, 山下潤]
通讯作者:
山下潤
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