Development of comprehensive cardiac regeneration strategies with human ES cells
Development of comprehensive cardiac regeneration strategies with human ES cells
批准号:
19390213
负责人:
YAMASHITA Jun
金额:
$11.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
代表者はマウスES細胞を用いて循環器系細胞を系統的に誘導できる新しい分化誘導系を開発した。本研究は、同システムを用いて、新たな心臓再生治療応用シーズを探索し、細胞・遺伝子・薬剤など新たな治療法を包括的に開拓することを目的とした。心筋細胞の自動能維持機構の解析、心筋及び心筋前駆細胞分化誘導効率を約10倍高める物質の同定、人工多能性幹細胞(iPS細胞)からの心血管分化誘導法の開発を行い、種々の心臓再生戦略のシーズ開発に成功した。
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Notchと beta-catenin シグナルによる新しい動脈内皮細胞分化誘導機構
通过Notch和β-连环蛋白信号诱导动脉内皮细胞分化的新机制
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[山水康平, 山下潤]
通讯作者:
山下潤
DOI:
10.1161/circulationaha.108.769562
发表时间:
2008-07-29
期刊:
CIRCULATION
影响因子:
37.8
作者:
[Narazaki, Genta, Uosaki, Hideki, Yamashita, Jun K.]
通讯作者:
Yamashita, Jun K.
Creations of biological pacemaker
生物起搏器的创作
DOI:
--
发表时间:
2009
期刊:
Inflammation and Regeneration 29
影响因子:
--
作者:
[R.Shirakawa, S.Fukai, M.Kawato, T.Higashi, H.Kondo, T., Narazaki G and Yamashita JK]
通讯作者:
Narazaki G and Yamashita JK
Recent Advances in Thrombosis and Hemostasis 2008. Part 5
血栓和止血的最新进展 2008 年。第 5 部分
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Terabayashi T, Funato Y, Fukuda M, Miki H, Yamashita JK]
通讯作者:
Yamashita JK
Converged signaling of Notch and beta-catenin induces differentiation of arterial endothelial cells from VEGFR2+ vascular progenitors
Notch 和 β-catenin 的聚合信号诱导动脉内皮细胞从 VEGFR2 血管祖细胞分化
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Yamamizu K, Yamashita JK]
通讯作者:
Yamashita JK
共 39 条
An empirical study on educational privatization and child poverty
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批准号:18K02425
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:YAMASHITA Jun
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依托单位:
Development of Practice System which is Focused on Skill of Realtime Adjustment for Oral Presentation.
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批准号:25560100
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2013
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负责人:YAMASHITA Jun
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依托单位:
Novel humoral factors regulating epigenomic status
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批准号:25670384
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2013
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负责人:YAMASHITA Jun
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依托单位:
A study on creation of environment-related regional innovation systems and transfers of environmental technologies in Europe
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批准号:24520893
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2012
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负责人:YAMASHITA Jun
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依托单位:
Novel mechanism regulating timing of cardiovascular cells with molecular linkage between PKA signaling and epigenome regulation
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批准号:24659389
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2012
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负责人:YAMASHITA Jun
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依托单位:
Development of a novel vascular-targeting therapy through stem cell research
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批准号:24390197
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.4万
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财政年份:2012
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负责人:YAMASHITA Jun
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依托单位:
Epigenetic regulation of "differentiation timing" of cardiovascular cells
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批准号:23659415
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2011
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负责人:YAMASHITA Jun
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依托单位:
The effects and the challenges for the future of school choice from the perspective of teachers
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批准号:23830069
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$2.25万
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财政年份:2011
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负责人:YAMASHITA Jun
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依托单位:
Development of the machine and cultivation system in rice cropping for labor saving and environmental preservation by using cloth mulch
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批准号:21580309
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2009
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负责人:YAMASHITA Jun
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依托单位:
A Study on a relationship between implementation/sustainability of regional policies and creation of social capitals in Europe
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批准号:21520797
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.58万
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财政年份:2009
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负责人:YAMASHITA Jun
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依托单位:
Development of a novel"Seed and Soil"cardiac regenerative strategy with ES/iPS cells
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批准号:21390239
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.4万
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财政年份:2009
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负责人:YAMASHITA Jun
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依托单位:
Development of an museum guide which is enable to give exhibited objects'information to observer.
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批准号:20605001
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2008
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负责人:YAMASHITA Jun
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依托单位:
A Study on changes in regional structure caused by regional policies towards sustainable development, and policy evaluation in Scandinavia
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批准号:19520680
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.83万
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财政年份:2007
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负责人:YAMASHITA Jun
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依托单位:
Development of a Range-Extender Type Hybrid System for Highly-Stable Farm Transport Machine
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批准号:19580294
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2007
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负责人:YAMASHITA Jun
-
依托单位:
Development of selective induction system for functionally specified cardiomyocytes using embryonic stem cells
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批准号:16390224
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
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财政年份:2004
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负责人:YAMASHITA Jun
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依托单位:
Development of Prognosis system for Farm Work Accident Prevention Based on Chaotic Dynamics of Human Ear Plethysmography
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批准号:15580221
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2003
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负责人:YAMASHITA Jun
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依托单位:
Development of Gantry Systems for Strawberry Cultivation
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批准号:12660233
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2000
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负责人:YAMASHITA Jun
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依托单位:
海外基金