Identification of receptor for cell-to-cell infection of HSV

HSV细胞间感染受体的鉴定

• 批准号: 15K15138
• 负责人: Arii Jun
• 金额: $ 2.33万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15K15138/
• 关键词: HSV; glycoprotein; 膜タンパク質; 細胞間感染; ウイルス; レセプター; 細胞間伝播; ヘルペスウイルス; 糖タンパク質

项目成果

Herpes simplex virus type 1 UL51 Protein Regulates Virion Morphogenesis in the Nucleus in a Cell type and Phosphorylation-Dependent Manner

单纯疱疹病毒 1 型 UL51 蛋白以细胞类型和磷酸化依赖性方式调节细胞核中病毒粒子的形态发生

• 发表时间: 2017
• 作者: Shinya Oda;Akihisa Kato;Naoto Koyanagi;Yuhei Maruzuru;Jun Arii and Yasushi Kawaguchi
• 通讯作者: Jun Arii and Yasushi Kawaguchi

HSV-1 UL34 is required for proper targeting of viral and cellular regulators for viral de-envelopment at the nuclear membrane

HSV-1 UL34 是正确靶向病毒和细胞调节因子以实现病毒在核膜解包膜所必需的

• 发表时间: 2016
• 作者: Fumio Maeda;Yoshitaka Hirohata;Jun Arii;Akihisa Kato;Yasushi Kawaguchi
• 通讯作者: Yasushi Kawaguchi

Akhisa Kato, Shinya Oda, Jun Arii, Yasushi Kawaguchi

加藤明沙、织田慎也、有井淳、川口靖

• 发表时间: 2015
• 作者: 丸鶴雄平;小栁直人;有井潤;加藤哲久;川口寧;Membrane deformation for HSV-1 secondary envelopment is mediated by its glycoproteins.;Phosphorylation of an HSV-1 Us8A promotes viral pathogenecity by regulating the ability of the virus to invade the CNS from peripheral sites.
• 通讯作者: Phosphorylation of an HSV-1 Us8A promotes viral pathogenecity by regulating the ability of the virus to invade the CNS from peripheral sites.

ESCRT-III mediates vesicle-mediated nuclear export and regulates the integrity of the inner nuclear membrane

ESCRT-III 介导囊泡介导的核输出并调节内核膜的完整性

• 发表时间: 2017
• 作者: Jun Arii;Mizuki Watanabe;Fumio Maeda;Yuhei Maruzuru;Naoto Koyanagi;Akihisa Kato and Yasushi Kawaguchi
• 通讯作者: Akihisa Kato and Yasushi Kawaguchi

Regulation of herpes simplex virus-2 UL13 protein kinase by phosphorylation is important for viral replication, pathogenic manifestations, and virulence in vivo

单纯疱疹病毒 2 UL13 蛋白激酶磷酸化调节对于病毒复制、致病表现和体内毒力非常重要

• 发表时间: 2017
• 作者: Naoto Koyanagi;Akihisa Kato;Yuhei Maruzuru;Jun Arii and Yasushi Kawaguchi
• 通讯作者: Jun Arii and Yasushi Kawaguchi