A Facility for High-Throughput, Functional Gene Discovery Using Arrayed Retroviral Expression Cloning

使用阵列逆转录病毒表达克隆进行高通量功能基因发现的设施

• 批准号: LE0668241
• 负责人: Prof Thomas Gonda
• 金额: $ 54.98万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0668241
• 关键词: Facility; Throughput; Functional; Gene; Discovery

The proposed facility will represent world-leading technology in functional genomics and provide Australian scientists with unique opportunities to identify genes involved in a broad range of biological processes. This will contribute to fundamental knowledge in mammalian biology, and equally importantly, is likely to identify genes involved in important health problems such as cancer, inflammatory disease, brain damage and diabetes. Such genes may in turn constitute targets against which new therapies may be developed. This endeavour will contribute to national research priorities in both the health and scientific/technological development arenas.

拟议的设施将代表功能基因组学的世界领先技术，并为澳大利亚科学家提供独特的机会，以确定参与广泛生物过程的基因。这将有助于哺乳动物生物学的基础知识，同样重要的是，很可能确定涉及重要健康问题的基因，如癌症，炎症性疾病，脑损伤和糖尿病。这些基因反过来又可以构成靶点，针对这些靶点可以开发新的疗法。这一努力将有助于在卫生和科学/技术发展领域的国家研究优先事项。