Regulation of local lymphocyte trafficking and its role during infection

局部淋巴细胞运输的调节及其在感染过程中的作用

• 批准号: DP0663084
• 负责人: Prof Jean-Pierre Scheerlinck
• 金额: $ 17.6万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0663084
• 关键词: Regulation; local; lymphocyte; trafficking; its

The study of early immune responses will contribute to the development of better vaccination strategies. In particular it will contribute by helping to understand the essential differences between reactogenicity and immunogenicity and how this relates to adjuvants. Using this understanding it will be possible to develop novel adjuvants that induce appropriate immunity with minimal side effects.

对早期免疫应答的研究将有助于制定更好的疫苗接种策略。特别是，它将有助于理解反应原性和免疫原性之间的本质区别，以及这与佐剂的关系。利用这种理解，将有可能开发新的佐剂，诱导适当的免疫力，副作用最小。