Development of electrophoretic co-deposition of bioactive and antibacterial ceramics with biodegradable polymers to produce novel composite coatings for biomedical applications

该项目旨在了解不同尺寸和形态的有机和无机颗粒在电泳共沉积过程中发生的基本现象，以获得在钛生物材料上获得生物活性和抗菌性能平衡的新型多组分生物降解涂层。特别是，将研究电火花放电的机理和动力学，以制备具有可剪裁微结构的均匀涂层。将对涂层进行表征，以提供对EPD参数-微/纳米结构-性能关系的基本了解。这项研究符合基础研究的标准，主要目的是系统地了解电沉积对多组分生物可降解涂层的微观结构(物相组成)和表面形貌的影响，以及涂层与基材的附着力、微观机械和摩擦学性能、生物活性和抗菌性以及电化学耐蚀性等众多性能。这一新知识不仅将有助于控制涂层的沉积过程，描述共沉积过程中聚合物与陶瓷颗粒之间的相互作用，而且还将有助于获得具有预期组织和性能的重复涂层。这些问题将显著提高材料科学和生物医学工程领域的知识水平。

The project aims to understand basic phenomena taking place during electrophoretic co-deposition of organic and inorganic particles with different size and morphology to obtain novel multicomponent biodegradable coatings with a balance of bioactive and antibacterial properties on titanium biomaterials. In particular, the mechanisms and kinetics of EPD will be investigated to fabricate homogeneous coatings with tailored microstructure. Characterisation of the coatings will be done to provide a fundamental understanding of the EPD parameters – micro/nanostructure – properties relationships. The proposed study complies the criteria of basic research and the main goal is to obtain a systematic, new knowledge about the influence of the EPD route on microstructure (phase composition) and surface topography of multicomponent biodegradable coatings as well as numerous properties, like coatings adhesion to the substrates, micro-mechanical and tribological properties, bioactivity and antibacterial properties as well as electrochemical corrosion resistance. This new knowledge will not only be useful for controlling the deposition process of coatings and to describe the interaction between the polymer and ceramic particles during co-deposition but also to obtain repetitive coatings with the intended microstructure and properties. These issues will provide a significant increase in the current state of knowledge in the field of materials science and biomedical engineering.