Bio-adaptive Coatings on Mg alloys

镁合金生物适应性涂层

• 批准号: 263858005
• 负责人: Professor Dr.-Ing. Aldo Boccaccini
• 金额: --
• 依托单位: Lehrstuhl für Korrosion und Oberflächentechnik
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/263858005?language=en
• 关键词: Bio; adaptive; Coatings; Mg; alloys

Magnesium and its alloys are possible candidates for biologically degradable biomaterials. They offer an interesting combination of resorbability, biocompatibility and mechanical stability compared with previous resorbable materials in medical application (polymers). Therefore Mg-materials are intensively studied: as potential temporary orthopaedic and cardiological implants as well as bone replacement materials. The use of this material fails due to the missing control of the corrosion rates, respectively due to the missing trust in the control.The aim of the project is to deliver a major contribution to the understanding of degradation of the coated substrates made of Mg alloys and to force the development of a new family of bio-adaptive coating. Especially the interactions and effects of a bioadaptive coating to the corrosion process will be analyzed. The interface between coating and substrate is significantly affecting not only the corrosion of the entire component but also the adhesion of the coating. This study produce in a first step the base for the use of bio-adaptive coatings onto orthopaedic implants made of Mg alloys and in a second step also for scaffolds as bone replacement.

镁及其合金是生物可降解生物材料的潜在候选材料。与以前在医疗应用中的可吸收材料（聚合物）相比，它们提供了可吸收性、生物相容性和机械稳定性的有趣组合。因此，镁材料被广泛研究：作为潜在的临时骨科和心脏植入物以及骨替代材料。由于缺乏对腐蚀速率的控制，这种材料的使用失败，分别是由于缺乏对控制的信任。该项目的目的是为了解镁合金涂层基板的降解做出重大贡献，并推动开发新的生物适应性涂层家族。重点分析了生物适应性涂层与腐蚀过程的相互作用和影响。涂层与基体之间的界面不仅对整个构件的腐蚀有显著影响，而且对涂层的附着力也有显著影响。这项研究的第一步为生物适应性涂层在镁合金矫形植入物上的应用提供了基础，第二步也为骨替代支架提供了基础。