Bio-adaptive Coatings on Mg alloys

镁及其合金是一种可生物降解的生物材料。与以前的医疗应用中的可吸收材料（聚合物）相比，它们提供了可吸收性、生物相容性和机械稳定性的有趣组合。因此，镁材料被广泛研究：作为潜在的临时骨科和心脏植入物以及骨替代材料。这种材料的使用失败是由于缺少对腐蚀速率的控制，分别由于缺少对控制的信任。该项目的目的是提供一个重大贡献的理解由镁合金制成的涂层基材的降解，并迫使一个新的家庭的生物适应性涂层的发展。特别是生物适应性涂层对腐蚀过程的相互作用和影响将被分析。涂层和基体之间的界面不仅对整个部件的腐蚀有显著影响，而且对涂层的附着力也有显著影响。本研究首先为镁合金骨科植入物的生物适应性涂层的使用奠定了基础，第二步也为骨替代支架奠定了基础。

Magnesium and its alloys are possible candidates for biologically degradable biomaterials. They offer an interesting combination of resorbability, biocompatibility and mechanical stability compared with previous resorbable materials in medical application (polymers). Therefore Mg-materials are intensively studied: as potential temporary orthopaedic and cardiological implants as well as bone replacement materials. The use of this material fails due to the missing control of the corrosion rates, respectively due to the missing trust in the control.The aim of the project is to deliver a major contribution to the understanding of degradation of the coated substrates made of Mg alloys and to force the development of a new family of bio-adaptive coating. Especially the interactions and effects of a bioadaptive coating to the corrosion process will be analyzed. The interface between coating and substrate is significantly affecting not only the corrosion of the entire component but also the adhesion of the coating. This study produce in a first step the base for the use of bio-adaptive coatings onto orthopaedic implants made of Mg alloys and in a second step also for scaffolds as bone replacement.