Bio-adaptive Coatings on Mg alloys

镁及其合金可能是生物可降解生物材料的候选材料。与以前的医疗应用中的可吸收材料(聚合物)相比，它们提供了可吸收、生物相容性和机械稳定性的有趣组合。因此，镁材料被广泛研究：作为矫形外科和心脏外科的临时性植入物以及骨替代材料。由于缺乏对腐蚀速率的控制，这种材料的使用失败，分别是由于对控制的信任缺失。该项目的目的是为理解镁合金涂层基材的降解做出重大贡献，并推动新的生物适应涂层家族的开发。特别是分析了生物适应性涂层对腐蚀过程的相互作用和影响。涂层与基材之间的界面不仅对整个构件的腐蚀有重要影响，而且对涂层的结合力也有很大影响。这项研究第一步为在镁合金制成的骨科植入物上使用生物适应涂层奠定了基础，第二步也为支架作为骨替代材料奠定了基础。

Magnesium and its alloys are possible candidates for biologically degradable biomaterials. They offer an interesting combination of resorbability, biocompatibility and mechanical stability compared with previous resorbable materials in medical application (polymers). Therefore Mg-materials are intensively studied: as potential temporary orthopaedic and cardiological implants as well as bone replacement materials. The use of this material fails due to the missing control of the corrosion rates, respectively due to the missing trust in the control.The aim of the project is to deliver a major contribution to the understanding of degradation of the coated substrates made of Mg alloys and to force the development of a new family of bio-adaptive coating. Especially the interactions and effects of a bioadaptive coating to the corrosion process will be analyzed. The interface between coating and substrate is significantly affecting not only the corrosion of the entire component but also the adhesion of the coating. This study produce in a first step the base for the use of bio-adaptive coatings onto orthopaedic implants made of Mg alloys and in a second step also for scaffolds as bone replacement.