強磁場環境が生物に与える影響に関する研究

强磁场环境对生物体影响的研究

• 批准号: 16651017
• 负责人: 冨永 伸明
• 金额: $ 1.98万
• 依托单位: Ariake National College of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Exploratory Research
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16651017/
• 关键词: 磁場; 超伝導マグネット; 線虫; メダカ

本研究課題では,磁場の生物に対する影響を評価することを目的として,定常強磁場による以下の実験を行った.最大10テスラの定常磁場を発生させることができる超伝導マグネット中で,線虫C. elegansおよび初期発生中のメダカ卵に対する10テスラの磁場を垂直方向に24および48時間曝露した.その後,線虫は発生,成長および繁殖力を5世代後まで観察した.また,メダカは孵化時間,成長,繁殖力を検討した.線虫は,卵,幼虫期(L1からL4期),および成虫期に曝露したものについて検討したが,成長,繁殖能の顕著な変化は見られなかった.また,系世代的な影響も確認できなかった.一方,メダカは発生初期卵を曝露したところ,発生過程においてコントロールとの違いは観察されなかったが,孵化までに要する日数がコントロールと比較して数日早くなる傾向が見られた.さらに,数回の曝露実験中に稚魚が成長するにつれ,遊泳および行動に異常をきたしたものが現れる場合があった.その遊泳と行動の異常は,魚体制御の傾きと頭を上にした縦泳ぎおよび遊泳中の突然筋肉が硬直して垂直方向に回転する行動であった.また,縦泳ぎをしたメダカは成魚まで成長しなかった.しかしながら,異常行動を示す雌雄ペアからの2世代目のメダカには異常行動をとるものは現れなかった.磁場方向・再現性および解剖学的な更なる検討が必要であるが,以上の結果から,強磁場環境は生物に影響を与える可能性があることが示され,その影響は遺伝子レベルではなく,おそらく神経系の発達などに強く影響を及ぼすと考えられ,高等な生物の発生時期などに顕著に現れる可能性が高いことが示唆された.

The problem of this study is that the magnetic field biological system has a significant effect on the purpose of the magnetic field, and the magnetic field is stable. The maximum 10-kilowatt stationary magnetic field has been exposed for 24 hours and 48 hours in the vertical direction of the 10-kilometer stationary magnetic field during the initial period of life of C. elegans. After a long period of time, the insects grow, and the fecundity of the larvae is observed after five generations. The incubation time, growth, fecundity and fecundity of oysters. The larva, egg, larval stage (L1, L4), the adult stage of the larva is exposed to the adult stage of the larva, and the larvae grow and reproduce. This is the shadow of generations to make sure that you are in love with others. On the one hand, the eggs in the early stages of life were exposed to severe diarrhea, and during the process of birth, the number of days of incubation was observed, and the number of days of incubation was several days earlier than that of the baby. It has been exposed several times that young children have grown up in the middle of the school, and swimming activities have been found to be in good health. The movement of swimming is very common, and the system is responsible for the sudden movement of muscles and muscles in the middle of the swim. Swimming, swimming and swimming. The regular activities of both sexes show that there are two generations of children in the family, and there are regular activities in each generation. It is necessary to improve the anatomy of the magnetic field in the direction of the magnetic field. The above results show that it is necessary to strengthen the magnetic field environment, the biological effects and the possibilities of the magnetic field environment. During the life cycle of advanced biology, there is a high probability that it is possible to instigate trouble.

项目成果

Short-term effects of endocrine-disrupting chemicals on the expression of estrogen-responsive genes in male medaka (Oryzias latipes)

• DOI: 10.1016/j.aquatox.2004.12.011
• 发表时间: 2005-04-30
• 期刊: AQUATIC TOXICOLOGY
• 影响因子: 4.5
• 作者: Yamaguchi, A;Ishibashi, H;Tominaga, N
• 通讯作者: Tominaga, N