MECHANISM OF MAINTENANCE OF POTASSIUM HOMEOSTASIS IN NERVOUS SYSTEM BY GLIAL-NEURONAL INTERACTION

K~+稳态至少维持了三个过程。电生理和电子显微镜研究表明，快速和中等处理分别是由于横跨雪旺细胞的微管系统的横向扩散和横向扩散所致。通过对酶分离的雪旺细胞进行全细胞膜片钳研究，发现慢过程与雪旺细胞的离子机制有关。我们发现至少有三种电压敏感电流：内向钙敏感外向K电流和在超极化电压下出现的内向整流电流。

The K^+ homeostasis was found to be maintained at least three processes. The fast and medium processed were revealed to be due to lateral diffusion and transversal diffusion through microtubular system across the Schwann cell, respectively from the electrophysiological and electron microscopic studies. The slow process was found to be related to ionic mechanism of the Schwann cell by whole cell-patch clamp studies on enzymatically isolated Schwann cells. We found at least three voltage sensitive currents ; inward Ca^<2+> -sensitive outward K^+ current, and inwardly rectifying current that appeared at hyperpolarizing voltages.