Epidemiological, clinical and experimental study on neurological, psychological and behavioral disturbances induced by alcohol.

酒精引起的神经、心理和行为障碍的流行病学、临床和实验研究。

• 批准号: 05670338
• 负责人: YOKOYAMA Kazuhito
• 金额: $ 1.47万
• 依托单位: University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05670338/
• 关键词: Drinking; Alcobol dependency; neurobehaviard effects; Sobriety; Reasons; Self-help group; 神経、精神および行動障害; 神経,精神および行動障害

Epidemiological, clinical and experimental studies were carried out on neurological, psychological and behavioral disturbances induced by alcohol, to clarify relationships between reasons for drinking and problem drinking behavior, sobriety factors, neurobehavioral effects in alcoholics, etc. The following findings were obtained.1.Factors affecting sobriety were examined by questionnaires among patients with alcohol dependency. A group of patients who had continued sobriety reported that they considered family, job and AA to be important.2.Reasons for drinking in relation to problem drinking were studied in a group of high school students. Five factors of reasons for drinking, viz. escapism, sociability, tension-reduction, acting like a man and home/enjoyment, were identified. The first three were found to be related to problem drinking behavior.3.Neurophysiological examinations were conducted on patients with alcohol dependency.The patients showed slowing of nerve conduction, changes in distribution of nerve conduction velocities and abnormal findings of ECG R-R interval variability.Research findings have been published in journals and monograph and presented at scientific meetings.

本研究从流行病学、临床和实验三个方面对酒精引起的神经、心理和行为障碍进行了研究，旨在阐明饮酒原因与问题饮酒行为、戒酒因素、神经行为效应等的关系。一组持续清醒的患者报告说，他们认为家庭、工作和AA是重要的。2.在一组高中生中研究了与问题饮酒有关的饮酒原因。饮酒原因的五个因素，即逃避现实，社交，减少紧张，像一个男人和家庭/享受。3.对酒精依赖患者进行神经生理学检查，发现神经传导减慢，神经传导速度分布改变，心电图R-R间期变异性异常，研究结果已发表在期刊和专著上，并在科学会议上发表。

项目成果

Murata, K.: "Autonomic neurotoxicity of alcohol assessed by heart rate variability" Journal of the Autonomic Nervous System. 48. 105-111 (1994)

Murata, K.：“通过心率变异性评估酒精的自主神经毒性”自主神经系统杂志。

荒記俊一: "南山堂" 産業保健マニュアル(第3版). 179-180,△187-189 (1995)

荒木俊一：《南山堂》工业健康手册（第3版）179-180，△187-189（1995年）。

荒記俊一: "環境因子による非顕性の神経・精神行動障害の評価方法と最近の知見" 日本衛生学雑誌. 50. 713-729 (1995)

Shunichi Araki：“环境因素引起的亚临床神经和心理行为障碍的评估方法和最新发现”日本卫生杂志 50. 713-729 (1995)。

横山 和仁: "飲酒動機が高校生の問題飲酒行動に及ぼす影響" 日衛誌. 51(1). 3-43 (1996)

Kazuhito Yokoyama：“饮酒动机对高中生问题饮酒行为的影响”，《日本杂志》51(1) (1996)。

横山 和仁: "四エチール鉛中毒 新臨床内科 コンパクト版" 医学書院, 514 (1994)

横山一仁：《四乙基铅中毒新临床内科精简版》 Igakushoin，514（1994）