Morphology and physiology of the afferent and efferent otolith neurons.

传入和传出耳石神经元的形态学和生理学。

• 批准号: 05671427
• 负责人: NAITO Yasushi
• 金额: $ 1.34万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05671427/
• 关键词: Otolith; Vestibular nerve; Afferent; Efferent; Brainstem; Saccule; Utricle; 耳石系遠心性; 求心性ニューロン; 前庭神経活動; 平衡斑感覚上皮; 内耳道内前庭神経; 神経標識物質

Cytochrome oxidase activity of primary vestibular afferent neurons in Scarpa's ganglion of the squirrel monkey was demonstrated. Negative correlation between the size of the neurons and their cytochrome oxidase activities was observed. Innervation patterns of primary vestibular neurons in the guinea pig utricule were examined with HRP method. Nerve fibers which do not bifurcate connect with type I hair cells in the striolar region, while those that do not bifurcate connect with type I and type II hair cells throughout the utricular maculae. Irregularly firing neurons with higher coefficient of variation had higher gain to tilt. Among the lateral tilt reactive neurons, ipsilateral tilt neurons were greater in number than contralateral neurons. A new method was developed for specific labeling of vestibular afferent and efferent neurons from selected vestibular end-organs of chinchillas using biocytin. In the dorsal region of the brainstem, the vestibular efferents that innervated the hor … More izontal semicircular canal were located more caudally than those innervating the saccule and were primarily on the contralateral side, while, in the reticular formation, saccular efferents were found more on the contralateral side and horizontal canal efferents were found bilaterally. The effect of caloric stimulation on the primary vestibular fibers originating from the otolith organ was investigated in the guinea pig. There was a tendency for neurons with increased firing rates increased firing rates to warm stimulation, while those whose rats increased to contralateral tilting had increased rates to cold stimulation. The caloric test thus examines not only the horizontal canal function but also the otolith function. Distortion product otoacoustic emission (DP-OAE) were recorded in human subjects, and the effect of contralateral sound stimulation on them was examined. DP-OAE was suppressed by contralateral sound stimulation on them was examined. DP-OAE was suppressed by contralateral sound stimulation, and this suppression disappeared after vestibular neurectomy. Less

本文报道了松鼠猴前庭初级传入神经元细胞色素氧化酶的活性。细胞色素氧化酶活性与神经元大小呈负相关。用HRP法观察了豚鼠椭圆囊内初级前庭神经元的神经支配方式。不分叉的神经纤维与纹状区的I型毛细胞连接，而不分叉的神经纤维与椭圆囊斑中的I型和II型毛细胞连接。变异系数越高的不规则放电神经元倾斜增益越大。在侧倾反应神经元中，同侧倾斜反应神经元的数量多于对侧。本研究建立了一种生物胞素标记毛丝鼠前庭终器传入和传出神经元的新方法。在脑干背侧区，支配马的前庭传出纤维 ...更多信息 在网状结构中，囊状传出纤维多见于对侧，水平管传出纤维见于双侧。本文观察了冷热刺激对豚鼠耳石器发出的初级前庭纤维的影响。有一种倾向，即神经元的放电频率增加，增加了发射率，以温暖的刺激，而那些大鼠增加到对侧倾斜增加率，以冷刺激。因此，冷热试验不仅检查水平耳道功能，而且检查耳石功能。本文记录了正常人的畸变产物耳声发射（DP-OAE），并观察了对侧声刺激对DP-OAE的影响。对侧声刺激可抑制DP-OAE。对侧声刺激可抑制DP-OAE，前庭神经切断后这种抑制消失。少

项目成果

Naito Y,Naito E,Honjo I,Shiomi Y,Tsuji J: "Labeling of vestibular afferent and efferent nerves from selected end-organs in chinchillas." Equilibrium Research. vol.53. 398-403 (1994)

Naito Y、Naito E、Honjo I、Shiomi Y、Tsuji J：“龙猫选定终末器官的前庭传入和传出神经的标记。”

辻 純: "モルモット耳石器の形態と機能" 耳鼻臨床. 87. 699-709 (1994)

Jun Tsuji：“豚鼠耳石器官的形态和功能”耳鼻喉科 87. 699-709 (1994)

内藤 泰: "チンチラ前庭求心及び遠心神経の選択的標識" Equilibrium Research. 53. 398-403 (1994)

Yasushi Naito：“龙猫前庭传入神经和传出神经的选择性标记”平衡研究 53. 398-403 (1994)。

Honrubia V,Hoffman LF,Newman A,Naito E,Naito Y: "Sensoritopic and topologic organization of the vestibular nerve." The Mammalian Cochlear Nuclei. 1993. 437-449

Honrubia V、Hoffman LF、Newman A、Naito E、Naito Y：“前庭神经的感觉和拓扑组织。”

Tsuji J,Naito Y,Takahashi H,Honjo I: "Effect of contralateral sound stimulation on human DP-OAE." Practica Otologica. vol.88. 159-163 (1995)

Tsuji J，Naito Y，Takahashi H，Honjo I：“对侧声音刺激对人类 DP-OAE 的影响。”