Quantification of relative coronary arterial stenosis

相对冠状动脉狭窄的量化

• 批准号: 62480294
• 负责人: HIROSE Hajime
• 金额: $ 4.48万
• 依托单位: Gifu University, School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480294/
• 关键词: coronary artery; coronary sclerosis; coronary angiography; 冠動脈狭窄度評価法; 冠動脈狭窄

This study was designed to develop a new method to gqantificate relative coronary arterial stenosis. The idea was based on that oppacity representing the volume of contrast medium was proportional to the relative stenosis of coronary artery. The system was consisted of coronary density analyzer (CDA) with a 1024^*1024 pixel matrix andan 8-bit gray scale. In tube-model experiments,% relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were affected by concentration of contrast medium.In coronary-model experiments, we evaluated three-dimensional reconstruction of the space-density curves of bi-palne coronary angiography. % relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were severly affected by wrong dicision of the coordinate axis.Thus densitometric analysis of % relative stenosis of coronary artery allowes three-dimensional assessment and might correlate with direct measurement of coronary arterial stenosis.

本研究旨在建立一种新的冠状动脉相对狭窄的定量方法。其基本思想是：造影剂的体积与冠状动脉的相对狭窄程度成正比。该系统由1024^*1024像素矩阵和8位灰度级的冠状动脉密度分析仪（CDA）组成。在管模型实验中，该CDA评估的相对狭窄%与冠状动脉狭窄的直接测量具有线性关系。在冠状动脉模型实验中，我们评价了双通道冠状动脉造影的空间-密度曲线的三维重建。用该CDA评估的相对狭窄%与冠状动脉狭窄的直接测量具有线性关系。因此，冠状动脉相对狭窄百分比的密度分析可以进行三维评估，并可能与冠状动脉狭窄的直接测量相关。