Quantification of relative coronary arterial stenosis

本研究旨在开发一种新的冠状动脉相对狭窄的定量方法。这一想法是基于表示造影剂体积的不透明度与冠状动脉的相对狭窄成正比。该系统由1024×1024像素矩阵的冠状动脉密度分析仪(CDA)和8位灰度级组成。在管状模型实验中，该CDA测量的相对狭窄率与直接测量的冠状动脉狭窄程度呈线性关系。这种关系受造影剂浓度的影响。在冠状动脉模型实验中，我们评估了双掌冠状动脉造影空间密度曲线的三维重建。CDA测定的相对狭窄率与直接测量的冠状动脉狭窄程度呈线性关系。这种关系受到坐标轴错误判断的严重影响。因此，冠状动脉相对狭窄率的密度计量学分析可以进行三维评估，并可能与直接测量冠状动脉狭窄相关。

This study was designed to develop a new method to gqantificate relative coronary arterial stenosis. The idea was based on that oppacity representing the volume of contrast medium was proportional to the relative stenosis of coronary artery. The system was consisted of coronary density analyzer (CDA) with a 1024^*1024 pixel matrix andan 8-bit gray scale. In tube-model experiments,% relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were affected by concentration of contrast medium.In coronary-model experiments, we evaluated three-dimensional reconstruction of the space-density curves of bi-palne coronary angiography. % relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were severly affected by wrong dicision of the coordinate axis.Thus densitometric analysis of % relative stenosis of coronary artery allowes three-dimensional assessment and might correlate with direct measurement of coronary arterial stenosis.