High performance liquid chromatography mass spectrometer (QqQ)

高效液相色谱质谱仪（QqQ）

• 批准号: 438263278
• 金额: --
• 依托单位: Bergische Universität Wuppertal
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2020
• 资助国家: 德国
• 起止时间: 2019-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/438263278?language=en
• 关键词: performance; liquid; chromatography; mass; spectrometer

Two-dimensional high-performance liquid chromatograph (LC) with a sensitive mass spectrometer (MS) is a key tool for the quantification of compounds in complex mixtures as selective and sensitive as possible. Thereby the two-dimensional liquid chromatography enables a high selectivity, and the mass spectrometer allows the quantification of small, medium and large molecules with extremely low detection limits due to its high resolution as well as the usage of fragmentation experiments. Currently, at the faculty of mathematics and natural science at the University of Wuppertal, no two-dimensional (ultra) high-performance liquid chromatography or a state-of-the-art mass spectrometer are available. Since Prof. Schebb, Prof. Bornhorst and Prof. Simon started their research at the University of Wuppertal a large number of research questions arose, which can only be answered by LC-MS. In order to address new joint research projects, the working groups have decided to apply for such a system

二维高效液相色谱仪（LC）与灵敏的质谱仪（MS）是一个关键的工具，用于定量的复杂混合物中的化合物尽可能的选择性和灵敏度。因此，二维液相色谱能够实现高选择性，并且质谱仪由于其高分辨率以及使用碎裂实验而允许以极低的检测限定量小分子、中等分子和大分子。目前，在伍珀塔尔大学数学和自然科学系，没有二维（超）高效液相色谱法或最先进的质谱仪。自从Schebb教授、Bornhorst教授和Simon教授在伍珀塔尔大学开始他们的研究以来，出现了大量的研究问题，这些问题只能通过LC-MS来回答。为了解决新的联合研究项目，工作组决定申请这样的系统