Evolutionary models and bioinformatic analyses of genetic variation in pathogens

病原体遗传变异的进化模型和生物信息学分析

• 批准号: DP0556732
• 负责人: Prof Mark Tanaka
• 金额: $ 18.39万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0556732
• 关键词: Evolutionary; models; bioinformatic; analyses; genetic

The benefits of this project are better preparedness for the ever-present threat of infectious disease spread and the stimulation of bioinformatic research in Australia. Epidemics such as the Influenza Pandemic of 1918, which killed over 20 million people, highlight the need to understand and track pathogens that can potentially cause such devastation. Along with the development of molecular technologies, it is important to maintain active creation of analytical methods that appropriately apply to growing databases. These include methods to understand genetic variation in pathogens. This project will help to keep Australia at the forefront of research in theoretical biology.

该项目的好处是更好地准备应对传染病传播的威胁，并刺激澳大利亚的生物信息学研究。1918年的流感大流行导致2000多万人死亡，这类流行病突出表明需要了解和追踪可能造成这种破坏的病原体。沿着分子技术的发展，保持分析方法的积极创造，适当地适用于不断增长的数据库是很重要的。这些包括了解病原体遗传变异的方法。该项目将有助于使澳大利亚保持在理论生物学研究的前沿。