Taste Sensor Using LB Membranes for Detecting Nonelectrolytes

使用 LB 膜检测非电解质的味觉传感器

• 批准号: 04650270
• 负责人: TOKO Kiyoshi
• 金额: $ 1.47万
• 依托单位: KYUSHU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04650270/
• 关键词: LB membrane; Taste sensor; High sensitivity; Lipid membrane; Chaos; Nonlinear dynamics; 味物質

The present study is aimed at the development of a taste sensor using a Langmuir-Blodgett (LB) membrane and also the utilization of nonlinear dynamics of lipid membranes for recognizing taste. The following results were obtained :1) The LB membrane responded to five kinds of taste substances (salty, sour, sweet, bitter, umami) in different ways. The sensitivity was higher than that of humans.2) The structural changes in lipid assemblies of a lipid-adsorbed membrane were observed using a special apparatus with a microscope when the self-sustained oscillation of membtane electric potential occurred.3) Chaos was induced by applying the d.c.electric current on the lipid membrane. The chaotic oscillation was changed by five kinds of taste substances in different ways. It was shown experimentally and theoretically that the nonlinear dynamics is effective for recognition of taste quality and magnitude.These results were found first by this study. Thus, the present study showed that the LB membranes are useful materials of a transducer of taste substances and that such a nonlinear dynamics as chaos is effective for recognizing taste in a manner similar to biological systems.

本研究的目的是开发一种味觉传感器，使用LB膜，也利用非线性动力学的脂质膜识别的味道。结果表明：1）LB膜对5种味觉物质（咸、酸、甜、苦、鲜）有不同的反应。2）用特殊的显微镜装置观察了膜电位自维持振荡时膜表面脂质组装体的结构变化; 3）在脂质膜上施加直流电流，诱导脂质组装体产生混沌。五种味觉物质以不同的方式改变了混沌振荡。从实验和理论上证明了非线性动力学对味觉质量和味觉大小的识别是有效的，这些结果是本研究首次发现的。因此，本研究表明，LB膜是有用的材料的传感器的味道物质和这种非线性动力学的混沌是有效的识别味道的方式类似于生物系统。

项目成果

K.Nomura: "A theoretical consideration of interactions between lipid membranes and taste substances" Sensors and Actuators. 4. 89-99 (1992)

K.Nomura：“脂膜和味觉物质之间相互作用的理论考虑”传感器和执行器。

秋山秀之: "LB法による味覚センサ用膜材料の開発" 計測自動制御学会論文集. 29. 1012-1014 (1993)

Hideyuki Akiyama：“使用 LB 方法开发味道传感器的膜材料”仪器与控制工程师协会会议记录 29. 1012-1014 (1993)。

Y.Saida: "Nonlinear dynamics in a theoretical model of excitable lipid membrane" Journal of the Physical Society of Japan. 62. 2934-2941 (1993)

Y.Saida：“可兴奋脂质膜理论模型中的非线性动力学”日本物理学会杂志。

Y.Saida: "Nonlinear dynamics in a theoretical model of excitable lipid membrane21GC04:Journal of the Physical Society of Japan" 62. 2934-2941 (1993)

Y.Saida：“可兴奋脂质膜理论模型中的非线性动力学21GC04：日本物理学会杂志”62. 2934-2941 (1993)

Y.Saida: "Chaos in excitable lipid membranes" Japanese Journal of Applied Physics. 32. 1859-1866 (1993)

Y.Saida：“可兴奋脂质膜中的混沌”日本应用物理学杂志。