Development of Kansei Biosensor

能够测量味觉和嗅觉的感性生物传感器是基于对味觉和嗅觉的分子水平人工受体的研究而开发的。我们成功地实现了一个高灵敏度的甜味传感器，输出约80mV，用于一种双糖，蔗糖，这是很难获得足够的膜电位变化。在玻璃或塑料衬底上制作味觉传感器芯片，以缩小检测部件的体积为目标，将其集成到LSI芯片上。在电化学传感器的基础上，利用脂质双分子层和自组装膜等薄膜修饰石英晶体振荡器，研制了一种人工嗅觉传感系统。

A Kansei biosensor that enables us to measure taste and smell is developed based on research of an artificial receptor at the molecular level for gustatory and olfactory senses. We have successfully achieved a high sensitive sweetness sensor, about 80mV output, for a disaccharide, sucrose, which was difficult to gain a sufficient membrane potential change. A taste sensor chip was fabricated on a glass or a plastic substrate, aiming at downsizing of a detecting part, and integrated it on LSI chips. In addition, an artificial olfactory sensing system was developed based on the electrochemical sensor and the quartz crystal oscillator modified with thin films such as a lipid bilayer and a self-assembled membrane.