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Biological rhythm and womens's night-shift work : an occupational and physiological study of effects and mechanisms.

生物节律和女性夜班工作：影响和机制的职业和生理研究。

基本信息

批准号：
04670300
负责人：
KOYAMA Akio
金额：
$ 1.34万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1993
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04670300/
关键词：
Biological rhythm Power spectral analysis Blood pressure Heart rate Night work Stress Sex 心電図 R-R間隔変動時系列解析最大エントロピー法

项目摘要

This study attempted 1) to establish a new method of time-series analysis for nonlinear physiological data , 2) to clarify the relationships between environmental, occupational and psycho-social factors of women's night-shift work utilizing a behavioral-medical approach, and 3) to elucidate the effects and their mechanisms on biological rhythm in the cardio-vascular system. Maximum entropy power spectral analysis and the least square method were performed to extract the periodic structure and the best fitting curves from physiological time-series data including blood pressure and heart rate recorded longer than 24 hours. As the residuals and their standard deviations between the raw data and the best fitting curves varied from only 10^<-8> to 10^<-9>, this method of analysis using artificial periodic functions is very effective to quantitatively evaluate changes of biological rhythm. Subjective fatigue symptoms at the end of work, and each phase (6 or 7 hours) of periods extracted from time-series data of blood pressure measured at 15 or 30 minutes interval, were similar for day- and nightshift workers. However, in the daytime after continuous night work, sleep with intermediate arousal accompanied by an increase in blood pressure and heart rate were observed. Psychological factors referred to as daily stress in addition to insufficient sleep may possibly have affected the biological rhythm. From the above, it is suggested that sleep in night-shift work and the reduction of daily stress are effective to maintain biological rhythm. Further, although the sexual differences of changes in biological rhythm by night-shift work were not clarified, the importance of health administration in the occupational fields is suggested, particulary in the recent process of the Ministry of Labor giving access to women to night-shift work.

本研究试图1)建立一种新的非线性生理数据的时间序列分析方法，2)用行为医学的方法阐明女性夜班工作的环境、职业和心理社会因素之间的关系，3)阐明这些因素对心血管系统生物节律的影响及其机制。采用最大熵功率谱分析和最小二乘法从超过24小时的血压、心率等生理时间序列数据中提取周期结构和最佳拟合曲线。由于原始数据与最佳拟合曲线之间的残差及其标准差仅在10^~(-8)~10^~(-9)~10^~(-9)之间变化，这种人工周期函数分析方法对于定量评价生物节律的变化是非常有效的。白班和夜班工人在工作结束时的主观疲劳症状，以及从每隔15分钟或30分钟测量血压的时间序列数据中提取的每个阶段(6或7小时)，都是相似的。然而，在夜间连续工作后的白天，观察到中度觉醒伴随着血压和心率的增加。除了睡眠不足之外，被称为日常压力的心理因素可能也影响了生物节律。由此可见，夜班工作中的睡眠和减少日常压力是维持生物节律的有效方法。此外，尽管没有阐明夜班工作改变生物节律的性别差异，但有人建议在职业领域进行卫生管理的重要性，特别是在劳动部最近允许妇女从事夜班工作的过程中。