Search for Antiallergic and Antidiabetic Constituents from Oriental Medicinal Foodstuffs

为了寻找新的具有生物活性的天然产物，我们一直致力于从东方药用食品中提取抗过敏和抗糖尿病成分的表征研究。在这些研究过程中，我们分离出了许多具有抗过敏和抗糖尿病活性的新化合物：1)从生姜（Shouga）中分离出两种抗过敏原理，6-shojail和6-gingerol；2)四种抗过敏二萜酮，三叶酮A、B、C、D；3)楤木（Aralia elata, Taranome）幼芽中5种降血糖皂苷：elatosides G、H、I、J、K；4)五种降血糖低聚糖苷，甜菜芥甙I、II、III、IV和V，从甜菜芥（Satoudaikon）的根和叶中提取；5)从Gymnema sylvestre （Gimunema）的叶子中提取的两种降糖苷，gymnemosides a和b；6)八种降血糖皂苷：叶黄素Ia、Ib、IIa、IIb、IIIa、IIIb、IV、V。

In search of new biologically active natural products, we have been engaged in characterization studies on antiallergic and antidiabetic constituents from oriental medicinal foodstuffs. During the course of these studies, we have isolated various new compounds having potent antiallergic and antidiabetic activities : i.e. 1) Two antiallergic principles, 6-shojail and 6-gingerol, from Zingiber officinale (Shouga) ; 2) Four antiallergic diterpene ketones, tirfoliones A,B,C,and D,from the tuber of Sagittaria trifolia (Kuwai) ; 3) Five hypoglycemic saponins, elatosides G,H,I,J,and K,from the young shoot of Aralia elata (Taranome) ; 4) Five hypoglycemic oligoglycosides, betavulgarosides I,II,III,IV,and V,from the roots and leaves of Beta vularis (Satoudaikon) ; 5) Two hypoglycemic glycosides, gymnemosides a and b, from the leaves of Gymnema sylvestre (Gimunema) ; 6) Eight hypoglycemic saponins escins Ia, Ib, IIa, IIb, IIIa, IIIb, IV,and V,from the seed of Aesculus hippocastanum (Tochinoki).